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Immunization with murine breast cancer cells treated with antisense oligodeoxynucleotides to type I insulin-like growth factor receptor induced an antitumoral effect mediated by a CD8+ response involving Fas/Fas ligand cytotoxic pathway.
Schillaci R, Salatino M, Cassataro J, Proietti CJ, Giambartolomei GH, Rivas MA, Carnevale RP, Charreau EH, Elizalde PV. Schillaci R, et al. Among authors: giambartolomei gh. J Immunol. 2006 Mar 15;176(6):3426-37. doi: 10.4049/jimmunol.176.6.3426. J Immunol. 2006. PMID: 16517711
Brucella abortus inhibits major histocompatibility complex class II expression and antigen processing through interleukin-6 secretion via Toll-like receptor 2.
Barrionuevo P, Cassataro J, Delpino MV, Zwerdling A, Pasquevich KA, García Samartino C, Wallach JC, Fossati CA, Giambartolomei GH. Barrionuevo P, et al. Among authors: giambartolomei gh. Infect Immun. 2008 Jan;76(1):250-62. doi: 10.1128/IAI.00949-07. Epub 2007 Nov 5. Infect Immun. 2008. PMID: 17984211 Free PMC article.
Brucella lipoproteins mimic dendritic cell maturation induced by Brucella abortus.
Zwerdling A, Delpino MV, Barrionuevo P, Cassataro J, Pasquevich KA, García Samartino C, Fossati CA, Giambartolomei GH. Zwerdling A, et al. Among authors: giambartolomei gh. Microbes Infect. 2008 Oct;10(12-13):1346-54. doi: 10.1016/j.micinf.2008.07.035. Epub 2008 Aug 12. Microbes Infect. 2008. PMID: 18761420 Free article.
Immunization with recombinant Brucella species outer membrane protein Omp16 or Omp19 in adjuvant induces specific CD4+ and CD8+ T cells as well as systemic and oral protection against Brucella abortus infection.
Pasquevich KA, Estein SM, García Samartino C, Zwerdling A, Coria LM, Barrionuevo P, Fossati CA, Giambartolomei GH, Cassataro J. Pasquevich KA, et al. Among authors: giambartolomei gh. Infect Immun. 2009 Jan;77(1):436-45. doi: 10.1128/IAI.01151-08. Epub 2008 Nov 3. Infect Immun. 2009. PMID: 18981242 Free PMC article.
Brucella abortus activates human neutrophils.
Zwerdling A, Delpino MV, Pasquevich KA, Barrionuevo P, Cassataro J, García Samartino C, Giambartolomei GH. Zwerdling A, et al. Among authors: giambartolomei gh. Microbes Infect. 2009 May-Jun;11(6-7):689-97. doi: 10.1016/j.micinf.2009.04.010. Epub 2009 Apr 17. Microbes Infect. 2009. PMID: 19376263 Free article.
Brucella abortus induces the secretion of proinflammatory mediators from glial cells leading to astrocyte apoptosis.
García Samartino C, Delpino MV, Pott Godoy C, Di Genaro MS, Pasquevich KA, Zwerdling A, Barrionuevo P, Mathieu P, Cassataro J, Pitossi F, Giambartolomei GH. García Samartino C, et al. Among authors: giambartolomei gh. Am J Pathol. 2010 Mar;176(3):1323-38. doi: 10.2353/ajpath.2010.090503. Epub 2010 Jan 21. Am J Pathol. 2010. PMID: 20093491 Free PMC article.
The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis.
Pasquevich KA, García Samartino C, Coria LM, Estein SM, Zwerdling A, Ibañez AE, Barrionuevo P, Oliveira FS, Carvalho NB, Borkowski J, Oliveira SC, Warzecha H, Giambartolomei GH, Cassataro J. Pasquevich KA, et al. Among authors: giambartolomei gh. J Immunol. 2010 May 1;184(9):5200-12. doi: 10.4049/jimmunol.0902209. Epub 2010 Mar 29. J Immunol. 2010. PMID: 20351187
97 results