Woutersen RA - Search Results

1

Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols.

Strikwold M, Spenkelink B, de Haan LHJ, Woutersen RA, Punt A, Rietjens IMCM. Strikwold M, et al. Among authors: woutersen ra. Arch Toxicol. 2017 May;91(5):2119-2133. doi: 10.1007/s00204-016-1881-x. Epub 2016 Nov 4. Arch Toxicol. 2017. PMID: 27815601 Free PMC article.

2

Modulatory effects of quercetin on proliferation and differentiation of the human colorectal cell line Caco-2.

Dihal AA, Woutersen RA, van Ommen B, Rietjens IM, Stierum RH. Dihal AA, et al. Among authors: woutersen ra. Cancer Lett. 2006 Jul 18;238(2):248-59. doi: 10.1016/j.canlet.2005.07.007. Epub 2005 Aug 29. Cancer Lett. 2006. PMID: 16129554

3

Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats.

Dihal AA, de Boer VC, van der Woude H, Tilburgs C, Bruijntjes JP, Alink GM, Rietjens IM, Woutersen RA, Stierum RH. Dihal AA, et al. Among authors: woutersen ra. J Nutr. 2006 Nov;136(11):2862-7. doi: 10.1093/jn/136.11.2862. J Nutr. 2006. PMID: 17056814 Free article.

4

Pathway and single gene analyses of inhibited Caco-2 differentiation by ascorbate-stabilized quercetin suggest enhancement of cellular processes associated with development of colon cancer.

Dihal AA, Tilburgs C, van Erk MJ, Rietjens IM, Woutersen RA, Stierum RH. Dihal AA, et al. Among authors: woutersen ra. Mol Nutr Food Res. 2007 Aug;51(8):1031-45. doi: 10.1002/mnfr.200600261. Mol Nutr Food Res. 2007. PMID: 17639512

5

Transcriptome and proteome profiling of colon mucosa from quercetin fed F344 rats point to tumor preventive mechanisms, increased mitochondrial fatty acid degradation and decreased glycolysis.

Dihal AA, van der Woude H, Hendriksen PJ, Charif H, Dekker LJ, Ijsselstijn L, de Boer VC, Alink GM, Burgers PC, Rietjens IM, Woutersen RA, Stierum RH. Dihal AA, et al. Among authors: woutersen ra. Proteomics. 2008 Jan;8(1):45-61. doi: 10.1002/pmic.200700364. Proteomics. 2008. PMID: 18095365

6

Relative developmental toxicity of glycol ether alkoxy acid metabolites in the embryonic stem cell test as compared with the in vivo potency of their parent compounds.

de Jong E, Louisse J, Verwei M, Blaauboer BJ, van de Sandt JJ, Woutersen RA, Rietjens IM, Piersma AH. de Jong E, et al. Among authors: woutersen ra. Toxicol Sci. 2009 Jul;110(1):117-24. doi: 10.1093/toxsci/kfp083. Epub 2009 Apr 28. Toxicol Sci. 2009. PMID: 19401353

7

Systematic construction of a conceptual minimal model of plasma cholesterol levels based on knockout mouse phenotypes.

van de Pas NC, Soffers AE, Freidig AP, van Ommen B, Woutersen RA, Rietjens IM, de Graaf AA. van de Pas NC, et al. Among authors: woutersen ra. Biochim Biophys Acta. 2010 Jun;1801(6):646-54. doi: 10.1016/j.bbalip.2010.02.009. Epub 2010 Feb 20. Biochim Biophys Acta. 2010. PMID: 20176131

8

The use of in vitro toxicity data and physiologically based kinetic modeling to predict dose-response curves for in vivo developmental toxicity of glycol ethers in rat and man.

Louisse J, de Jong E, van de Sandt JJ, Blaauboer BJ, Woutersen RA, Piersma AH, Rietjens IM, Verwei M. Louisse J, et al. Among authors: woutersen ra. Toxicol Sci. 2010 Dec;118(2):470-84. doi: 10.1093/toxsci/kfq270. Epub 2010 Sep 10. Toxicol Sci. 2010. PMID: 20833708

9

The respiratory allergen glutaraldehyde in the local lymph node assay: sensitization by skin exposure, but not by inhalation.

van Triel JJ, van Bree BW, Roberts DW, Muijser H, Duistermaat E, Woutersen RA, Kuper CF. van Triel JJ, et al. Among authors: woutersen ra. Toxicology. 2011 Jan 11;279(1-3):115-22. doi: 10.1016/j.tox.2010.09.018. Epub 2010 Oct 7. Toxicology. 2011. PMID: 20933045

10

A physiologically-based kinetic model for the prediction of plasma cholesterol concentrations in the mouse.

van de Pas NC, Woutersen RA, van Ommen B, Rietjens IM, de Graaf AA. van de Pas NC, et al. Among authors: woutersen ra. Biochim Biophys Acta. 2011 May;1811(5):333-42. doi: 10.1016/j.bbalip.2011.02.002. Epub 2011 Feb 12. Biochim Biophys Acta. 2011. PMID: 21320632

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