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In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.
Suzuki K, Tsunekawa Y, Hernandez-Benitez R, Wu J, Zhu J, Kim EJ, Hatanaka F, Yamamoto M, Araoka T, Li Z, Kurita M, Hishida T, Li M, Aizawa E, Guo S, Chen S, Goebl A, Soligalla RD, Qu J, Jiang T, Fu X, Jafari M, Esteban CR, Berggren WT, Lajara J, Nuñez-Delicado E, Guillen P, Campistol JM, Matsuzaki F, Liu GH, Magistretti P, Zhang K, Callaway EM, Zhang K, Belmonte JC. Suzuki K, et al. Among authors: liu gh. Nature. 2016 Dec 1;540(7631):144-149. doi: 10.1038/nature20565. Epub 2016 Nov 16. Nature. 2016. PMID: 27851729 Free PMC article.
Nitric oxide destabilizes Pias3 and regulates sumoylation.
Qu J, Liu GH, Wu K, Han P, Wang P, Li J, Zhang X, Chen C. Qu J, et al. Among authors: liu gh. PLoS One. 2007 Oct 31;2(10):e1085. doi: 10.1371/journal.pone.0001085. PLoS One. 2007. PMID: 17987106 Free PMC article.
Lipin proteins form homo- and hetero-oligomers.
Liu GH, Qu J, Carmack AE, Kim HB, Chen C, Ren H, Morris AJ, Finck BN, Harris TE. Liu GH, et al. Biochem J. 2010 Nov 15;432(1):65-76. doi: 10.1042/BJ20100584. Biochem J. 2010. PMID: 20735359 Free PMC article.
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome.
Liu GH, Barkho BZ, Ruiz S, Diep D, Qu J, Yang SL, Panopoulos AD, Suzuki K, Kurian L, Walsh C, Thompson J, Boue S, Fung HL, Sancho-Martinez I, Zhang K, Yates J 3rd, Izpisua Belmonte JC. Liu GH, et al. Nature. 2011 Apr 14;472(7342):221-5. doi: 10.1038/nature09879. Epub 2011 Feb 23. Nature. 2011. PMID: 21346760 Free PMC article.
Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs.
Liu GH, Suzuki K, Qu J, Sancho-Martinez I, Yi F, Li M, Kumar S, Nivet E, Kim J, Soligalla RD, Dubova I, Goebl A, Plongthongkum N, Fung HL, Zhang K, Loring JF, Laurent LC, Izpisua Belmonte JC. Liu GH, et al. Cell Stem Cell. 2011 Jun 3;8(6):688-94. doi: 10.1016/j.stem.2011.04.019. Epub 2011 May 19. Cell Stem Cell. 2011. PMID: 21596650 Free PMC article.
953 results