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The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs.
Mandoli A, Singh AA, Prange KHM, Tijchon E, Oerlemans M, Dirks R, Ter Huurne M, Wierenga ATJ, Janssen-Megens EM, Berentsen K, Sharifi N, Kim B, Matarese F, Nguyen LN, Hubner NC, Rao NA, van den Akker E, Altucci L, Vellenga E, Stunnenberg HG, Martens JHA. Mandoli A, et al. Among authors: van den akker e. Cell Rep. 2016 Nov 15;17(8):2087-2100. doi: 10.1016/j.celrep.2016.08.082. Cell Rep. 2016. PMID: 27851970 Free article.
Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets.
van Oorschot R, Hansen M, Koornneef JM, Marneth AE, Bergevoet SM, van Bergen MGJM, van Alphen FPJ, van der Zwaan C, Martens JHA, Vermeulen M, Jansen PWTC, Baltissen MPA, Gorkom BAPL, Janssen H, Jansen JH, von Lindern M, Meijer AB, van den Akker E, van der Reijden BA. van Oorschot R, et al. Among authors: van der zwaan c, van den akker e, van der reijden ba, van alphen fpj, van bergen mgjm. Haematologica. 2019 Jul;104(7):1460-1472. doi: 10.3324/haematol.2018.194555. Epub 2019 Jan 17. Haematologica. 2019. PMID: 30655368 Free PMC article.
CBFβ-MYH11 interferes with megakaryocyte differentiation via modulating a gene program that includes GATA2 and KLF1.
Yi G, Mandoli A, Jussen L, Tijchon E, van Bergen MGJM, Cordonnier G, Hansen M, Kim B, Nguyen LN, Jansen PWTC, Vermeulen M, van der Reijden B, van den Akker E, Bond J, Martens JHA. Yi G, et al. Among authors: van der reijden b, van den akker e, van bergen mgjm. Blood Cancer J. 2019 Mar 8;9(3):33. doi: 10.1038/s41408-019-0194-8. Blood Cancer J. 2019. PMID: 30850577 Free PMC article.
Specific proteome changes in platelets from individuals with GATA1-, GFI1B-, and RUNX1-linked bleeding disorders.
Van Bergen MGJM, Marneth AE, Hoogendijk AJ, Van Alphen FPJ, Van den Akker E, Laros-Van Gorkom BAP, Hoeks M, Simons A, De Munnik SA, Janssen JJWM, Martens JHA, Jansen JH, Meijer AB, Van der Reijden BA. Van Bergen MGJM, et al. Among authors: van den akker e, van der reijden ba, van alphen fpj. Blood. 2021 Jul 8;138(1):86-90. doi: 10.1182/blood.2020008118. Blood. 2021. PMID: 33690840 Free article.
GFI1B and LSD1 repress myeloid traits during megakaryocyte differentiation.
Venhuizen J, van Bergen MGJM, Bergevoet SM, Gilissen D, Spruijt CG, Wingens L, van den Akker E, Vermeulen M, Jansen JH, Martens JHA, van der Reijden BA. Venhuizen J, et al. Among authors: van den akker e, van der reijden ba, van bergen mgjm. Commun Biol. 2024 Mar 28;7(1):374. doi: 10.1038/s42003-024-06090-z. Commun Biol. 2024. PMID: 38548886 Free PMC article.
SMIM1 underlies the Vel blood group and influences red blood cell traits.
Cvejic A, Haer-Wigman L, Stephens JC, Kostadima M, Smethurst PA, Frontini M, van den Akker E, Bertone P, Bielczyk-Maczyńska E, Farrow S, Fehrmann RS, Gray A, de Haas M, Haver VG, Jordan G, Karjalainen J, Kerstens HH, Kiddle G, Lloyd-Jones H, Needs M, Poole J, Soussan AA, Rendon A, Rieneck K, Sambrook JG, Schepers H, Silljé HHW, Sipos B, Swinkels D, Tamuri AU, Verweij N, Watkins NA, Westra HJ, Stemple D, Franke L, Soranzo N, Stunnenberg HG, Goldman N, van der Harst P, van der Schoot CE, Ouwehand WH, Albers CA. Cvejic A, et al. Among authors: van den akker e, van der harst p, van der schoot ce. Nat Genet. 2013 May;45(5):542-545. doi: 10.1038/ng.2603. Epub 2013 Apr 7. Nat Genet. 2013. PMID: 23563608 Free PMC article.
Generation and characterization of human iPSC line MML-6838-Cl2 from mobilized peripheral blood derived megakaryoblasts.
Hansen M, Varga E, Wüst T, Brouwer N, Beauchemin H, Mellink C, van der Kevie-Kersemaekers AM, Möröy T, van der Reijden B, von Lindern M, van den Akker E. Hansen M, et al. Among authors: van der kevie kersemaekers am, van der reijden b, van den akker e. Stem Cell Res. 2017 Jan;18:26-28. doi: 10.1016/j.scr.2016.12.004. Epub 2016 Dec 10. Stem Cell Res. 2017. PMID: 28395797 Free article.
Generation and characterization of a human iPSC line SANi005-A containing the gray platelet associated heterozygous mutation p.Q287* in GFI1B.
Hansen M, Varga E, Wüst T, Mellink C, van der Kevie-Kersemaekers AM, Marneth AE, von Lindern M, van der Reijden B, van den Akker E. Hansen M, et al. Among authors: van der kevie kersemaekers am, van der reijden b, van den akker e. Stem Cell Res. 2017 Dec;25:34-37. doi: 10.1016/j.scr.2017.10.008. Epub 2017 Oct 12. Stem Cell Res. 2017. PMID: 29055225 Free article.
432 results