Chen W - Search Results

1

Identification of Human Anti-HIV gp160 Monoclonal Antibodies That Make Effective Immunotoxins.

Pincus SH, Song K, Maresh GA, Hamer DH, Dimitrov DS, Chen W, Zhang MY, Ghetie VF, Chan-Hui PY, Robinson JE, Vitetta ES. Pincus SH, et al. Among authors: chen w. J Virol. 2017 Jan 18;91(3):e01955-16. doi: 10.1128/JVI.01955-16. Print 2017 Feb 1. J Virol. 2017. PMID: 27852851 Free PMC article.

2

Human monoclonal antibodies and engineered antibody domains as HIV-1 entry inhibitors.

Chen W, Dimitrov DS. Chen W, et al. Curr Opin HIV AIDS. 2009 Mar;4(2):112-7. doi: 10.1097/COH.0b013e328322f95e. Curr Opin HIV AIDS. 2009. PMID: 19339949 Free PMC article. Review.

3

Engineered single human CD4 domains as potent HIV-1 inhibitors and components of vaccine immunogens.

Chen W, Feng Y, Gong R, Zhu Z, Wang Y, Zhao Q, Dimitrov DS. Chen W, et al. J Virol. 2011 Sep;85(18):9395-405. doi: 10.1128/JVI.05119-11. Epub 2011 Jun 29. J Virol. 2011. PMID: 21715496 Free PMC article.

4

Monoclonal antibody-based candidate therapeutics against HIV type 1.

Chen W, Dimitrov DS. Chen W, et al. AIDS Res Hum Retroviruses. 2012 May;28(5):425-34. doi: 10.1089/AID.2011.0226. Epub 2011 Sep 23. AIDS Res Hum Retroviruses. 2012. PMID: 21827278 Free PMC article. Review.

5

Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies.

Zhu Z, Qin HR, Chen W, Zhao Q, Shen X, Schutte R, Wang Y, Ofek G, Streaker E, Prabakaran P, Fouda GG, Liao HX, Owens J, Louder M, Yang Y, Klaric KA, Moody MA, Mascola JR, Scott JK, Kwong PD, Montefiori D, Haynes BF, Tomaras GD, Dimitrov DS. Zhu Z, et al. Among authors: chen w. J Virol. 2011 Nov;85(21):11401-8. doi: 10.1128/JVI.05312-11. Epub 2011 Aug 31. J Virol. 2011. PMID: 21880764 Free PMC article.

6

Exceptionally potent and broadly cross-reactive, bispecific multivalent HIV-1 inhibitors based on single human CD4 and antibody domains.

Chen W, Feng Y, Prabakaran P, Ying T, Wang Y, Sun J, Macedo CD, Zhu Z, He Y, Polonis VR, Dimitrov DS. Chen W, et al. J Virol. 2014 Jan;88(2):1125-39. doi: 10.1128/JVI.02566-13. Epub 2013 Nov 6. J Virol. 2014. PMID: 24198429 Free PMC article.

7

Potent In Vivo NK Cell-Mediated Elimination of HIV-1-Infected Cells Mobilized by a gp120-Bispecific and Hexavalent Broadly Neutralizing Fusion Protein.

Bardhi A, Wu Y, Chen W, Li W, Zhu Z, Zheng JH, Wong H, Jeng E, Jones J, Ochsenbauer C, Kappes JC, Dimitrov DS, Ying T, Goldstein H. Bardhi A, et al. Among authors: chen w. J Virol. 2017 Sep 27;91(20):e00937-17. doi: 10.1128/JVI.00937-17. Print 2017 Oct 15. J Virol. 2017. PMID: 28794022 Free PMC article.

8

Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers.

Chen W, Zhu Z, Feng Y, Dimitrov DS. Chen W, et al. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17121-6. doi: 10.1073/pnas.0805297105. Epub 2008 Oct 28. Proc Natl Acad Sci U S A. 2008. PMID: 18957538 Free PMC article.

9

Bifunctional fusion proteins of the human engineered antibody domain m36 with human soluble CD4 are potent inhibitors of diverse HIV-1 isolates.

Chen W, Xiao X, Wang Y, Zhu Z, Dimitrov DS. Chen W, et al. Antiviral Res. 2010 Oct;88(1):107-15. doi: 10.1016/j.antiviral.2010.08.004. Epub 2010 Aug 13. Antiviral Res. 2010. PMID: 20709110 Free PMC article.

10

Characterization of germline antibody libraries from human umbilical cord blood and selection of monoclonal antibodies to viral envelope glycoproteins: Implications for mechanisms of immune evasion and design of vaccine immunogens.

Chen W, Streaker ED, Russ DE, Feng Y, Prabakaran P, Dimitrov DS. Chen W, et al. Biochem Biophys Res Commun. 2012 Jan 27;417(4):1164-9. doi: 10.1016/j.bbrc.2011.12.089. Epub 2011 Dec 27. Biochem Biophys Res Commun. 2012. PMID: 22226962 Free PMC article.

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