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Discovery of BPR1K871, a quinazoline based, multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation.
Hsu YC, Coumar MS, Wang WC, Shiao HY, Ke YY, Lin WH, Kuo CC, Chang CW, Kuo FM, Chen PY, Wang SY, Li AS, Chen CH, Kuo PC, Chen CP, Wu MH, Huang CL, Yen KJ, Chang YI, Hsu JT, Chen CT, Yeh TK, Song JS, Shih C, Hsieh HP. Hsu YC, et al. Among authors: chen ct, chen ch, chen py, chen cp. Oncotarget. 2016 Dec 27;7(52):86239-86256. doi: 10.18632/oncotarget.13369. Oncotarget. 2016. PMID: 27863392 Free PMC article.
Novel indole-based peroxisome proliferator-activated receptor agonists: design, SAR, structural biology, and biological activities.
Mahindroo N, Huang CF, Peng YH, Wang CC, Liao CC, Lien TW, Chittimalla SK, Huang WJ, Chai CH, Prakash E, Chen CP, Hsu TA, Peng CH, Lu IL, Lee LH, Chang YW, Chen WC, Chou YC, Chen CT, Goparaju CM, Chen YS, Lan SJ, Yu MC, Chen X, Chao YS, Wu SY, Hsieh HP. Mahindroo N, et al. Among authors: chen ct, chen wc, chen cp, chen ys, chen x. J Med Chem. 2005 Dec 29;48(26):8194-208. doi: 10.1021/jm0506930. J Med Chem. 2005. PMID: 16366601
Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach.
Wu YS, Coumar MS, Chang JY, Sun HY, Kuo FM, Kuo CC, Chen YJ, Chang CY, Hsiao CL, Liou JP, Chen CP, Yao HT, Chiang YK, Tan UK, Chen CT, Chu CY, Wu SY, Yeh TK, Lin CY, Hsieh HP. Wu YS, et al. Among authors: chen yj, chen ct, chen cp. J Med Chem. 2009 Aug 13;52(15):4941-5. doi: 10.1021/jm900060s. J Med Chem. 2009. PMID: 19586033
Antitumor activities and pharmacokinetics of silatecans DB-67 and DB-91.
Yeh TK, Li CM, Chen CP, Chuu JJ, Huang CL, Wang HS, Shen CC, Lee TY, Chang CY, Chang CM, Chao YS, Lin CT, Chang JY, Chen CT. Yeh TK, et al. Among authors: chen ct, chen cp. Pharmacol Res. 2010 Feb;61(2):108-15. doi: 10.1016/j.phrs.2009.07.005. Epub 2009 Jul 28. Pharmacol Res. 2010. PMID: 19643180
Intravenous paclitaxel against metastasis of human gastric tumors of diffuse type.
Tuan TF, Tsai ML, Yeh KC, Huang HC, Chung CT, Huang CL, Han CH, Chen CP, Wang MH, Shen CC, Lai YK, Lee WS, Hwang LL, Chen CT. Tuan TF, et al. Among authors: chen ct, chen cp. Cancer Chemother Pharmacol. 2010 Sep;66(4):773-83. doi: 10.1007/s00280-009-1222-3. Epub 2010 Jan 1. Cancer Chemother Pharmacol. 2010. PMID: 20044750
2,022 results