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Interferon-driven deletion of antiviral B cells at the onset of chronic infection.
Fallet B, Narr K, Ertuna YI, Remy M, Sommerstein R, Cornille K, Kreutzfeldt M, Page N, Zimmer G, Geier F, Straub T, Pircher H, Larimore K, Greenberg PD, Merkler D, Pinschewer DD. Fallet B, et al. Among authors: merkler d. Sci Immunol. 2016 Oct 21;1(4):eaah6817. doi: 10.1126/sciimmunol.aah6817. Sci Immunol. 2016. PMID: 27872905 Free PMC article.
Impaired antibody response causes persistence of prototypic T cell-contained virus.
Bergthaler A, Flatz L, Verschoor A, Hegazy AN, Holdener M, Fink K, Eschli B, Merkler D, Sommerstein R, Horvath E, Fernandez M, Fitsche A, Senn BM, Verbeek JS, Odermatt B, Siegrist CA, Pinschewer DD. Bergthaler A, et al. Among authors: merkler d. PLoS Biol. 2009 Apr 7;7(4):e1000080. doi: 10.1371/journal.pbio.1000080. PLoS Biol. 2009. PMID: 19355789 Free PMC article.
T cell-dependence of Lassa fever pathogenesis.
Flatz L, Rieger T, Merkler D, Bergthaler A, Regen T, Schedensack M, Bestmann L, Verschoor A, Kreutzfeldt M, Brück W, Hanisch UK, Günther S, Pinschewer DD. Flatz L, et al. Among authors: merkler d. PLoS Pathog. 2010 Mar 26;6(3):e1000836. doi: 10.1371/journal.ppat.1000836. PLoS Pathog. 2010. PMID: 20360949 Free PMC article.
Targeted ablation of oligodendrocytes triggers axonal damage.
Ghosh A, Manrique-Hoyos N, Voigt A, Schulz JB, Kreutzfeldt M, Merkler D, Simons M. Ghosh A, et al. Among authors: merkler d. PLoS One. 2011;6(7):e22735. doi: 10.1371/journal.pone.0022735. Epub 2011 Jul 27. PLoS One. 2011. PMID: 21818378 Free PMC article.
The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses.
Bonilla WV, Fröhlich A, Senn K, Kallert S, Fernandez M, Johnson S, Kreutzfeldt M, Hegazy AN, Schrick C, Fallon PG, Klemenz R, Nakae S, Adler H, Merkler D, Löhning M, Pinschewer DD. Bonilla WV, et al. Among authors: merkler d. Science. 2012 Feb 24;335(6071):984-9. doi: 10.1126/science.1215418. Epub 2012 Feb 9. Science. 2012. PMID: 22323740
260 results