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Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease.
Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernández-Checa JC. Torres S, et al. Among authors: levade t. Redox Biol. 2017 Apr;11:60-72. doi: 10.1016/j.redox.2016.11.010. Epub 2016 Nov 20. Redox Biol. 2017. PMID: 27888692 Free PMC article.
Acid Ceramidase Deficiency in Mice Results in a Broad Range of Central Nervous System Abnormalities.
Sikora J, Dworski S, Jones EE, Kamani MA, Micsenyi MC, Sawada T, Le Faouder P, Bertrand-Michel J, Dupuy A, Dunn CK, Xuan ICY, Casas J, Fabrias G, Hampson DR, Levade T, Drake RR, Medin JA, Walkley SU. Sikora J, et al. Among authors: levade t. Am J Pathol. 2017 Apr;187(4):864-883. doi: 10.1016/j.ajpath.2016.12.005. Am J Pathol. 2017. PMID: 28342444 Free PMC article.
Activity-Based Imaging of Acid Ceramidase in Living Cells.
Ordóñez YF, Abad JL, Aseeri M, Casas J, Garcia V, Casasampere M, Schuchman EH, Levade T, Delgado A, Triola G, Fabrias G. Ordóñez YF, et al. Among authors: levade t. J Am Chem Soc. 2019 May 15;141(19):7736-7742. doi: 10.1021/jacs.8b11687. Epub 2019 May 2. J Am Chem Soc. 2019. PMID: 31030513
β-Galactosylceramidase Promotes Melanoma Growth via Modulation of Ceramide Metabolism.
Belleri M, Paganini G, Coltrini D, Ronca R, Zizioli D, Corsini M, Barbieri A, Grillo E, Calza S, Bresciani R, Maiorano E, Mastropasqua MG, Annese T, Giacomini A, Ribatti D, Casas J, Levade T, Fabrias G, Presta M. Belleri M, et al. Among authors: levade t. Cancer Res. 2020 Nov 15;80(22):5011-5023. doi: 10.1158/0008-5472.CAN-19-3382. Epub 2020 Sep 30. Cancer Res. 2020. PMID: 32998995
299 results