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Drug screening for ALS using patient-specific induced pluripotent stem cells.
Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H. Egawa N, et al. Among authors: yamamoto t. Sci Transl Med. 2012 Aug 1;4(145):145ra104. doi: 10.1126/scitranslmed.3004052. Sci Transl Med. 2012. PMID: 22855461
A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions.
Minami I, Yamada K, Otsuji TG, Yamamoto T, Shen Y, Otsuka S, Kadota S, Morone N, Barve M, Asai Y, Tenkova-Heuser T, Heuser JE, Uesugi M, Aiba K, Nakatsuji N. Minami I, et al. Among authors: yamamoto t. Cell Rep. 2012 Nov 29;2(5):1448-60. doi: 10.1016/j.celrep.2012.09.015. Epub 2012 Oct 25. Cell Rep. 2012. PMID: 23103164 Free article.
A fasting-responsive signaling pathway that extends life span in C. elegans.
Uno M, Honjoh S, Matsuda M, Hoshikawa H, Kishimoto S, Yamamoto T, Ebisuya M, Yamamoto T, Matsumoto K, Nishida E. Uno M, et al. Among authors: yamamoto t. Cell Rep. 2013 Jan 31;3(1):79-91. doi: 10.1016/j.celrep.2012.12.018. Epub 2013 Jan 24. Cell Rep. 2013. PMID: 23352664 Free article.
KLF4 N-terminal variance modulates induced reprogramming to pluripotency.
Kim SI, Oceguera-Yanez F, Hirohata R, Linker S, Okita K, Yamada Y, Yamamoto T, Yamanaka S, Woltjen K. Kim SI, et al. Among authors: yamamoto t. Stem Cell Reports. 2015 Apr 14;4(4):727-43. doi: 10.1016/j.stemcr.2015.02.004. Epub 2015 Mar 12. Stem Cell Reports. 2015. PMID: 25772473 Free PMC article.
Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells.
Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, Woltjen K, Nakagawa M, Yamamoto T, Takahashi K, Yamanaka S, Saitou M. Sasaki K, et al. Among authors: yamamoto t. Cell Stem Cell. 2015 Aug 6;17(2):178-94. doi: 10.1016/j.stem.2015.06.014. Epub 2015 Jul 16. Cell Stem Cell. 2015. PMID: 26189426 Free article.
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