Damha MJ - Search Results

1

Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1.

Clark NE, Katolik A, Roberts KM, Taylor AB, Holloway SP, Schuermann JP, Montemayor EJ, Stevens SW, Fitzpatrick PF, Damha MJ, Hart PJ. Clark NE, et al. Among authors: damha mj. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14727-14732. doi: 10.1073/pnas.1612729114. Epub 2016 Dec 6. Proc Natl Acad Sci U S A. 2016. PMID: 27930312 Free PMC article.

2

Branchpoint sugar stereochemistry determines the hydrolytic susceptibility of branched RNA fragments by the yeast debranching enzyme (YDBR).

Carriero S, Mangos MM, Agha KA, Noronha AM, Damha MJ. Carriero S, et al. Among authors: damha mj. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1599-602. doi: 10.1081/NCN-120023043. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565475

3

Template-mediated synthesis of lariat RNA and DNA.

Carriero S, Damha MJ. Carriero S, et al. Among authors: damha mj. J Org Chem. 2003 Oct 31;68(22):8328-38. doi: 10.1021/jo035002r. J Org Chem. 2003. PMID: 14575454

4

Synthesis, characterization, and biological properties of small branched RNA fragments containing chiral (Rp and Sp) 2',5'-phosphorothioate linkages.

Mourani R, Damha MJ. Mourani R, et al. Among authors: damha mj. Nucleosides Nucleotides Nucleic Acids. 2006;25(2):203-29. doi: 10.1080/15257770500447004. Nucleosides Nucleotides Nucleic Acids. 2006. PMID: 16541962

5

Studies on the hydrolytic stability of 2'-fluoroarabinonucleic acid (2'F-ANA).

Watts JK, Katolik A, Viladoms J, Damha MJ. Watts JK, et al. Among authors: damha mj. Org Biomol Chem. 2009 May 7;7(9):1904-10. doi: 10.1039/b900443b. Epub 2009 Mar 19. Org Biomol Chem. 2009. PMID: 19590787

6

Regiospecific solid-phase synthesis of branched oligoribonucleotides that mimic intronic lariat RNA intermediates.

Katolik A, Johnsson R, Montemayor E, Lackey JG, Hart PJ, Damha MJ. Katolik A, et al. Among authors: damha mj. J Org Chem. 2014 Feb 7;79(3):963-75. doi: 10.1021/jo4024182. J Org Chem. 2014. PMID: 24401015

7

A homolog of lariat-debranching enzyme modulates turnover of branched RNA.

Garrey SM, Katolik A, Prekeris M, Li X, York K, Bernards S, Fields S, Zhao R, Damha MJ, Hesselberth JR. Garrey SM, et al. Among authors: damha mj. RNA. 2014 Aug;20(8):1337-48. doi: 10.1261/rna.044602.114. Epub 2014 Jun 11. RNA. 2014. PMID: 24919400 Free PMC article.

8

Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1.

Montemayor EJ, Katolik A, Clark NE, Taylor AB, Schuermann JP, Combs DJ, Johnsson R, Holloway SP, Stevens SW, Damha MJ, Hart PJ. Montemayor EJ, et al. Among authors: damha mj. Nucleic Acids Res. 2014;42(16):10845-55. doi: 10.1093/nar/gku725. Epub 2014 Aug 14. Nucleic Acids Res. 2014. PMID: 25123664 Free PMC article.

9

Design, Synthesis, and Properties of Phosphoramidate 2',5'-Linked Branched RNA: Toward the Rational Design of Inhibitors of the RNA Lariat Debranching Enzyme.

Tago N, Katolik A, Clark NE, Montemayor EJ, Seio K, Sekine M, Hart PJ, Damha MJ. Tago N, et al. Among authors: damha mj. J Org Chem. 2015 Oct 16;80(20):10108-18. doi: 10.1021/acs.joc.5b01719. Epub 2015 Sep 30. J Org Chem. 2015. PMID: 26378468 Free PMC article.

10

Fluorescent Branched RNAs for High-Throughput Analysis of Dbr1 Enzyme Kinetics and Inhibition.

Katolik A, Clark NE, Tago N, Montemayor EJ, Hart PJ, Damha MJ. Katolik A, et al. Among authors: damha mj. ACS Chem Biol. 2017 Mar 17;12(3):622-627. doi: 10.1021/acschembio.6b00971. Epub 2017 Jan 18. ACS Chem Biol. 2017. PMID: 28055181

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