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Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy.
Huang Q, Li F, Liu X, Li W, Shi W, Liu FF, O'Sullivan B, He Z, Peng Y, Tan AC, Zhou L, Shen J, Han G, Wang XJ, Thorburn J, Thorburn A, Jimeno A, Raben D, Bedford JS, Li CY. Huang Q, et al. Among authors: wang xj. Nat Med. 2011 Jul 3;17(7):860-6. doi: 10.1038/nm.2385. Nat Med. 2011. PMID: 21725296 Free PMC article.
Loss of transforming growth factor beta type II receptor increases aggressive tumor behavior and reduces survival in lung adenocarcinoma and squamous cell carcinoma.
Malkoski SP, Haeger SM, Cleaver TG, Rodriguez KJ, Li H, Lu SL, Feser WJ, Barón AE, Merrick D, Lighthall JG, Ijichi H, Franklin W, Wang XJ. Malkoski SP, et al. Among authors: wang xj. Clin Cancer Res. 2012 Apr 15;18(8):2173-83. doi: 10.1158/1078-0432.CCR-11-2557. Epub 2012 Mar 7. Clin Cancer Res. 2012. PMID: 22399565 Free PMC article.
Preventive and therapeutic effects of Smad7 on radiation-induced oral mucositis.
Han G, Bian L, Li F, Cotrim A, Wang D, Lu J, Deng Y, Bird G, Sowers A, Mitchell JB, Gutkind JS, Zhao R, Raben D, ten Dijke P, Refaeli Y, Zhang Q, Wang XJ. Han G, et al. Among authors: wang xj, wang d. Nat Med. 2013 Apr;19(4):421-8. doi: 10.1038/nm.3118. Epub 2013 Mar 10. Nat Med. 2013. PMID: 23475202 Free PMC article.
Hedgehog signaling alters reliance on EGF receptor signaling and mediates anti-EGFR therapeutic resistance in head and neck cancer.
Keysar SB, Le PN, Anderson RT, Morton JJ, Bowles DW, Paylor JJ, Vogler BW, Thorburn J, Fernandez P, Glogowska MJ, Takimoto SM, Sehrt DB, Gan GN, Eagles-Soukup JR, Serracino H, Hirsch FR, Lucia MS, Thorburn A, Song JI, Wang XJ, Jimeno A. Keysar SB, et al. Among authors: wang xj. Cancer Res. 2013 Jun 1;73(11):3381-92. doi: 10.1158/0008-5472.CAN-12-4047. Epub 2013 Apr 10. Cancer Res. 2013. PMID: 23576557 Free PMC article.
A patient tumor transplant model of squamous cell cancer identifies PI3K inhibitors as candidate therapeutics in defined molecular bins.
Keysar SB, Astling DP, Anderson RT, Vogler BW, Bowles DW, Morton JJ, Paylor JJ, Glogowska MJ, Le PN, Eagles-Soukup JR, Kako SL, Takimoto SM, Sehrt DB, Umpierrez A, Pittman MA, Macfadden SM, Helber RM, Peterson S, Hausman DF, Said S, Leem TH, Goddard JA, Arcaroli JJ, Messersmith WA, Robinson WA, Hirsch FR, Varella-Garcia M, Raben D, Wang XJ, Song JI, Tan AC, Jimeno A. Keysar SB, et al. Among authors: wang xj. Mol Oncol. 2013 Aug;7(4):776-90. doi: 10.1016/j.molonc.2013.03.004. Epub 2013 Apr 4. Mol Oncol. 2013. PMID: 23607916 Free PMC article.
Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.
White RA, Neiman JM, Reddi A, Han G, Birlea S, Mitra D, Dionne L, Fernandez P, Murao K, Bian L, Keysar SB, Goldstein NB, Song N, Bornstein S, Han Z, Lu X, Wisell J, Li F, Song J, Lu SL, Jimeno A, Roop DR, Wang XJ. White RA, et al. Among authors: wang xj. J Clin Invest. 2013 Oct;123(10):4390-404. doi: 10.1172/JCI65856. Epub 2013 Sep 3. J Clin Invest. 2013. PMID: 23999427 Free PMC article.
Knockdown of EphB1 receptor decreases medulloblastoma cell growth and migration and increases cellular radiosensitization.
Bhatia S, Baig NA, Timofeeva O, Pasquale EB, Hirsch K, MacDonald TJ, Dritschilo A, Lee YC, Henkemeyer M, Rood B, Jung M, Wang XJ, Kool M, Rodriguez O, Albanese C, Karam SD. Bhatia S, et al. Among authors: wang xj. Oncotarget. 2015 Apr 20;6(11):8929-46. doi: 10.18632/oncotarget.3369. Oncotarget. 2015. PMID: 25879388 Free PMC article.
3,448 results