Chen A - Search Results

1

Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer.

He Y, Peng S, Wang J, Chen H, Cong X, Chen A, Hu M, Qin M, Wu H, Gao S, Wang L, Wang X, Yi Z, Liu M. He Y, et al. Among authors: chen a, chen h. Nat Commun. 2016 Dec 13;7:13122. doi: 10.1038/ncomms13122. Nat Commun. 2016. PMID: 27959342 Free PMC article.

2

Design and optimization of novel hydroxamate-based histone deacetylase inhibitors of Bis-substituted aromatic amides bearing potent activities against tumor growth and metastasis.

Yang F, Zhang T, Wu H, Yang Y, Liu N, Chen A, Li Q, Li J, Qin L, Jiang B, Wang X, Pang X, Yi Z, Liu M, Chen Y. Yang F, et al. Among authors: chen a, chen y. J Med Chem. 2014 Nov 26;57(22):9357-69. doi: 10.1021/jm5012148. Epub 2014 Nov 12. J Med Chem. 2014. PMID: 25360834

3

Development of a validated LC-MS/MS method for the determination of ailanthone in rat plasma with application to pharmacokinetic study.

Chen A, Qin X, Lu J, Yi Z, Liu M, Wang X. Chen A, et al. J Pharm Biomed Anal. 2015 Jan;102:514-8. doi: 10.1016/j.jpba.2014.10.022. Epub 2014 Oct 31. J Pharm Biomed Anal. 2015. PMID: 25433911

4

LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity.

Qin M, Peng S, Liu N, Hu M, He Y, Li G, Chen H, He Y, Chen A, Wang X, Liu M, Chen Y, Yi Z. Qin M, et al. Among authors: chen a, chen h, chen y. J Pharmacol Exp Ther. 2015 Dec;355(3):473-83. doi: 10.1124/jpet.115.225912. Epub 2015 Sep 16. J Pharmacol Exp Ther. 2015. PMID: 26377911

5

Evaluation of enzyme inhibition kinetics in drug-drug interactions.

Chen A, Qin X, Tang Y, Liu M, Wang X. Chen A, et al. Chem Biol Interact. 2014 Oct 5;222:133-4. doi: 10.1016/j.cbi.2014.10.010. Epub 2014 Oct 23. Chem Biol Interact. 2014. PMID: 25451570

6

Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach.

Chen A, Zhou X, Tang S, Liu M, Wang X. Chen A, et al. Sci Rep. 2016 Jun 22;6:28482. doi: 10.1038/srep28482. Sci Rep. 2016. PMID: 27329697 Free PMC article.

7

Assessment of the inhibition risk of shikonin on cytochrome P450 via cocktail inhibition assay.

Tang S, Chen A, Zhou X, Zeng L, Liu M, Wang X. Tang S, et al. Among authors: chen a. Toxicol Lett. 2017 Nov 5;281:74-83. doi: 10.1016/j.toxlet.2017.09.014. Epub 2017 Sep 21. Toxicol Lett. 2017. PMID: 28941798

8

Evaluation of the inhibition risk of shikonin on human and rat UDP-glucuronosyltransferases (UGT) through the cocktail approach.

Cheng Y, Tang S, Chen A, Zhang Y, Liu M, Wang X. Cheng Y, et al. Among authors: chen a. Toxicol Lett. 2019 Sep 15;312:214-221. doi: 10.1016/j.toxlet.2019.05.017. Epub 2019 May 23. Toxicol Lett. 2019. PMID: 31128210

9

Plant natural product plumbagin presents potent inhibitory effect on human cytochrome P450 2J2 enzyme.

Lu J, Liu D, Zhou X, Chen A, Jiang Z, Ye X, Liu M, Wang X. Lu J, et al. Among authors: chen a. Phytomedicine. 2018 Jan 15;39:137-145. doi: 10.1016/j.phymed.2017.12.026. Epub 2017 Dec 26. Phytomedicine. 2018. PMID: 29433675

10

Effects of cucurbitacin e, a tetracyclic triterpene compound from Cucurbitaceae, on the pharmacokinetics and pharmacodynamics of warfarin in rats.

Ding T, Zhang Y, Chen A, Tang Y, Liu M, Wang X. Ding T, et al. Among authors: chen a. Basic Clin Pharmacol Toxicol. 2015 May;116(5):385-9. doi: 10.1111/bcpt.12329. Epub 2014 Oct 13. Basic Clin Pharmacol Toxicol. 2015. PMID: 25250504 Free article.

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