Ruiz i Altaba A - Search Results

1

Long-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer Cells.

Seth C, Mas C, Conod A, Mueller J, Siems K, Kuciak M, Borges I, Ruiz i Altaba A. Seth C, et al. Among authors: ruiz i altaba a. PLoS One. 2016 Dec 14;11(12):e0168170. doi: 10.1371/journal.pone.0168170. eCollection 2016. PLoS One. 2016. PMID: 27973612 Free PMC article.

2

A novel genome-wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT-TCF pathway modulators TMED3 and SOX12.

Duquet A, Melotti A, Mishra S, Malerba M, Seth C, Conod A, Ruiz i Altaba A. Duquet A, et al. Among authors: ruiz i altaba a. EMBO Mol Med. 2014 Jul;6(7):882-901. doi: 10.15252/emmm.201303799. EMBO Mol Med. 2014. PMID: 24920608 Free PMC article.

3

The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer.

Melotti A, Mas C, Kuciak M, Lorente-Trigos A, Borges I, Ruiz i Altaba A. Melotti A, et al. Among authors: ruiz i altaba a. EMBO Mol Med. 2014 Oct;6(10):1263-78. doi: 10.15252/emmm.201404084. EMBO Mol Med. 2014. PMID: 25143352 Free PMC article.

4

Metastases and Colon Cancer Tumor Growth Display Divergent Responses to Modulation of Canonical WNT Signaling.

Seth C, Ruiz i Altaba A. Seth C, et al. Among authors: ruiz i altaba a. PLoS One. 2016 Mar 3;11(3):e0150697. doi: 10.1371/journal.pone.0150697. eCollection 2016. PLoS One. 2016. PMID: 26939070 Free PMC article.

5

Interference with HH-GLI signaling inhibits prostate cancer.

Stecca B, Mas C, Ruiz i Altaba A. Stecca B, et al. Among authors: ruiz i altaba a. Trends Mol Med. 2005 May;11(5):199-203. doi: 10.1016/j.molmed.2005.03.004. Trends Mol Med. 2005. PMID: 15882606 Review.

6

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion.

Varnat F, Duquet A, Malerba M, Zbinden M, Mas C, Gervaz P, Ruiz i Altaba A. Varnat F, et al. Among authors: ruiz i altaba a. EMBO Mol Med. 2009 Sep;1(6-7):338-51. doi: 10.1002/emmm.200900039. EMBO Mol Med. 2009. PMID: 20049737 Free PMC article.

7

Small molecule modulation of HH-GLI signaling: current leads, trials and tribulations.

Mas C, Ruiz i Altaba A. Mas C, et al. Among authors: ruiz i altaba a. Biochem Pharmacol. 2010 Sep 1;80(5):712-23. doi: 10.1016/j.bcp.2010.04.016. Epub 2010 Apr 20. Biochem Pharmacol. 2010. PMID: 20412786 Review.

8

In vivo epigenetic reprogramming of primary human colon cancer cells enhances metastases.

Singovski G, Bernal C, Kuciak M, Siegl-Cachedenier I, Conod A, Ruiz i Altaba A. Singovski G, et al. Among authors: ruiz i altaba a. J Mol Cell Biol. 2016 Apr;8(2):157-73. doi: 10.1093/jmcb/mjv034. Epub 2015 Jun 1. J Mol Cell Biol. 2016. PMID: 26031752 Free PMC article.

9

Chimeric NANOG repressors inhibit glioblastoma growth in vivo in a context-dependent manner.

Kuciak M, Mas C, Borges I, Sánchez-Gómez P, Ruiz I Altaba A. Kuciak M, et al. Among authors: ruiz i altaba a. Sci Rep. 2019 Mar 7;9(1):3891. doi: 10.1038/s41598-019-39473-y. Sci Rep. 2019. PMID: 30846719 Free PMC article.

10

The Gli code: an information nexus regulating cell fate, stemness and cancer.

Ruiz i Altaba A, Mas C, Stecca B. Ruiz i Altaba A, et al. Trends Cell Biol. 2007 Sep;17(9):438-47. doi: 10.1016/j.tcb.2007.06.007. Epub 2007 Sep 12. Trends Cell Biol. 2007. PMID: 17845852 Free PMC article. Review.

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