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Page 1
Rapid Chagas Disease Drug Target Discovery Using Directed Evolution in Drug-Sensitive Yeast.
Ottilie S, Goldgof GM, Calvet CM, Jennings GK, LaMonte G, Schenken J, Vigil E, Kumar P, McCall LI, Lopes ES, Gunawan F, Yang J, Suzuki Y, Siqueira-Neto JL, McKerrow JH, Amaro RE, Podust LM, Durrant JD, Winzeler EA. Ottilie S, et al. Among authors: jennings gk. ACS Chem Biol. 2017 Feb 17;12(2):422-434. doi: 10.1021/acschembio.6b01037. Epub 2016 Dec 23. ACS Chem Biol. 2017. PMID: 27977118 Free PMC article.
Biological evaluation and structure-activity relationships of imidazole-based compounds as antiprotozoal agents.
Saccoliti F, Madia VN, Tudino V, De Leo A, Pescatori L, Messore A, De Vita D, Scipione L, Brun R, Kaiser M, Mäser P, Calvet CM, Jennings GK, Podust LM, Costi R, Di Santo R. Saccoliti F, et al. Among authors: jennings gk. Eur J Med Chem. 2018 Aug 5;156:53-60. doi: 10.1016/j.ejmech.2018.06.063. Epub 2018 Jun 28. Eur J Med Chem. 2018. PMID: 30006174
Design, Synthesis, and Biological Evaluation of New 1-(Aryl-1 H-pyrrolyl)(phenyl)methyl-1 H-imidazole Derivatives as Antiprotozoal Agents.
Saccoliti F, Madia VN, Tudino V, De Leo A, Pescatori L, Messore A, De Vita D, Scipione L, Brun R, Kaiser M, Mäser P, Calvet CM, Jennings GK, Podust LM, Pepe G, Cirilli R, Faggi C, Di Marco A, Battista MR, Summa V, Costi R, Di Santo R. Saccoliti F, et al. Among authors: jennings gk. J Med Chem. 2019 Feb 14;62(3):1330-1347. doi: 10.1021/acs.jmedchem.8b01464. Epub 2019 Jan 23. J Med Chem. 2019. PMID: 30615444
Biophysical characterization of Aptenodytes forsteri cytochrome P450 aromatase.
Zarate-Perez F, Velázquez-Fernández JB, Jennings GK, Shock LS, Lyons CE, Hackett JC. Zarate-Perez F, et al. Among authors: jennings gk. J Inorg Biochem. 2018 Jul;184:79-87. doi: 10.1016/j.jinorgbio.2018.04.002. Epub 2018 Apr 7. J Inorg Biochem. 2018. PMID: 29684698 Free PMC article.
N-Heterocyclic Carbene Capture by Cytochrome P450 3A4.
Jennings GK, Ritchie CM, Shock LS, Lyons CE, Hackett JC. Jennings GK, et al. Mol Pharmacol. 2016 Jul;90(1):42-51. doi: 10.1124/mol.116.103721. Epub 2016 Apr 28. Mol Pharmacol. 2016. PMID: 27126611 Free PMC article.
65 results