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Selective ablation of mast cells or basophils reduces peanut-induced anaphylaxis in mice.
Reber LL, Marichal T, Mukai K, Kita Y, Tokuoka SM, Roers A, Hartmann K, Karasuyama H, Nadeau KC, Tsai M, Galli SJ. Reber LL, et al. Among authors: roers a. J Allergy Clin Immunol. 2013 Oct;132(4):881-8.e1-11. doi: 10.1016/j.jaci.2013.06.008. Epub 2013 Aug 1. J Allergy Clin Immunol. 2013. PMID: 23915716 Free PMC article.
Different activation signals induce distinct mast cell degranulation strategies.
Gaudenzio N, Sibilano R, Marichal T, Starkl P, Reber LL, Cenac N, McNeil BD, Dong X, Hernandez JD, Sagi-Eisenberg R, Hammel I, Roers A, Valitutti S, Tsai M, Espinosa E, Galli SJ. Gaudenzio N, et al. Among authors: roers a. J Clin Invest. 2016 Oct 3;126(10):3981-3998. doi: 10.1172/JCI85538. Epub 2016 Sep 19. J Clin Invest. 2016. PMID: 27643442 Free PMC article.
Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis.
Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, Reber LL, Pirottin D, Kim J, Chambon P, Roers A, Antoine N, Kawakami Y, Kawakami T, Bureau F, Tam SY, Tsai M, Galli SJ. Marichal T, et al. Among authors: roers a. J Clin Invest. 2016 Dec 1;126(12):4497-4515. doi: 10.1172/JCI86359. Epub 2016 Nov 7. J Clin Invest. 2016. PMID: 27820702 Free PMC article.
Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome.
Stackowicz J, Gaudenzio N, Serhan N, Conde E, Godon O, Marichal T, Starkl P, Balbino B, Roers A, Bruhns P, Jönsson F, Moguelet P, Georgin-Lavialle S, Broderick L, Hoffman HM, Galli SJ, Reber LL. Stackowicz J, et al. Among authors: roers a. J Exp Med. 2021 Oct 4;218(10):e20201466. doi: 10.1084/jem.20201466. Epub 2021 Sep 3. J Exp Med. 2021. PMID: 34477811 Free PMC article.
E-Cadherin restricts mast cell degranulation in mice.
Klewer T, Bakic L, Müller-Reichert T, Kiewisz R, Jessberger G, Kiessling N, Roers A, Jessberger R. Klewer T, et al. Among authors: roers a. Eur J Immunol. 2022 Jan;52(1):44-53. doi: 10.1002/eji.202049087. Epub 2021 Oct 20. Eur J Immunol. 2022. PMID: 34606636 Free article.
The transcription factor MAZR preferentially acts as a transcriptional repressor in mast cells and plays a minor role in the regulation of effector functions in response to FcεRI stimulation.
Abramova A, Sakaguchi S, Schebesta A, Hassan H, Boucheron N, Valent P, Roers A, Ellmeier W. Abramova A, et al. Among authors: roers a. PLoS One. 2013 Oct 17;8(10):e77677. doi: 10.1371/journal.pone.0077677. eCollection 2013. PLoS One. 2013. PMID: 24204913 Free PMC article.
A20-deficient mast cells exacerbate inflammatory responses in vivo.
Heger K, Fierens K, Vahl JC, Aszodi A, Peschke K, Schenten D, Hammad H, Beyaert R, Saur D, van Loo G, Roers A, Lambrecht BN, Kool M, Schmidt-Supprian M. Heger K, et al. Among authors: roers a. PLoS Biol. 2014 Jan;12(1):e1001762. doi: 10.1371/journal.pbio.1001762. Epub 2014 Jan 14. PLoS Biol. 2014. PMID: 24453940 Free PMC article.
142 results