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Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates.
Henderson SJ, Konkar A, Hornigold DC, Trevaskis JL, Jackson R, Fritsch Fredin M, Jansson-Löfmark R, Naylor J, Rossi A, Bednarek MA, Bhagroo N, Salari H, Will S, Oldham S, Hansen G, Feigh M, Klein T, Grimsby J, Maguire S, Jermutus L, Rondinone CM, Coghlan MP. Henderson SJ, et al. Among authors: bednarek ma. Diabetes Obes Metab. 2016 Dec;18(12):1176-1190. doi: 10.1111/dom.12735. Epub 2016 Aug 15. Diabetes Obes Metab. 2016. PMID: 27377054 Free PMC article.
LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor.
Ge X, Yang H, Bednarek MA, Galon-Tilleman H, Chen P, Chen M, Lichtman JS, Wang Y, Dalmas O, Yin Y, Tian H, Jermutus L, Grimsby J, Rondinone CM, Konkar A, Kaplan DD. Ge X, et al. Among authors: bednarek ma. Cell Metab. 2018 Feb 6;27(2):461-469.e6. doi: 10.1016/j.cmet.2017.10.016. Epub 2017 Dec 7. Cell Metab. 2018. PMID: 29233536 Free article.
A novel glucagon-like peptide 1/glucagon receptor dual agonist improves steatohepatitis and liver regeneration in mice.
Valdecantos MP, Pardo V, Ruiz L, Castro-Sánchez L, Lanzón B, Fernández-Millán E, García-Monzón C, Arroba AI, González-Rodríguez Á, Escrivá F, Álvarez C, Rupérez FJ, Barbas C, Konkar A, Naylor J, Hornigold D, Santos AD, Bednarek M, Grimsby J, Rondinone CM, Valverde ÁM. Valdecantos MP, et al. Hepatology. 2017 Mar;65(3):950-968. doi: 10.1002/hep.28962. Epub 2017 Jan 30. Hepatology. 2017. PMID: 27880981
64 results