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CXCR2 expression in tumor cells is a poor prognostic factor and promotes invasion and metastasis in lung adenocarcinoma.
Saintigny P, Massarelli E, Lin S, Ahn YH, Chen Y, Goswami S, Erez B, O'Reilly MS, Liu D, Lee JJ, Zhang L, Ping Y, Behrens C, Solis Soto LM, Heymach JV, Kim ES, Herbst RS, Lippman SM, Wistuba II, Hong WK, Kurie JM, Koo JS. Saintigny P, et al. Among authors: goswami s. Cancer Res. 2013 Jan 15;73(2):571-82. doi: 10.1158/0008-5472.CAN-12-0263. Epub 2012 Nov 30. Cancer Res. 2013. PMID: 23204236 Free PMC article.
Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression.
Chen L, Gibbons DL, Goswami S, Cortez MA, Ahn YH, Byers LA, Zhang X, Yi X, Dwyer D, Lin W, Diao L, Wang J, Roybal J, Patel M, Ungewiss C, Peng D, Antonia S, Mediavilla-Varela M, Robertson G, Suraokar M, Welsh JW, Erez B, Wistuba II, Chen L, Peng D, Wang S, Ullrich SE, Heymach JV, Kurie JM, Qin FX. Chen L, et al. Among authors: goswami s. Nat Commun. 2014 Oct 28;5:5241. doi: 10.1038/ncomms6241. Nat Commun. 2014. PMID: 25348003 Free PMC article.
Immune Checkpoint Therapies in Prostate Cancer.
Goswami S, Aparicio A, Subudhi SK. Goswami S, et al. Cancer J. 2016 Mar-Apr;22(2):117-20. doi: 10.1097/PPO.0000000000000176. Cancer J. 2016. PMID: 27111907 Free PMC article. Review.
Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma.
Goswami S, Walle T, Cornish AE, Basu S, Anandhan S, Fernandez I, Vence L, Blando J, Zhao H, Yadav SS, Ott M, Kong LY, Heimberger AB, de Groot J, Sepesi B, Overman M, Kopetz S, Allison JP, Pe'er D, Sharma P. Goswami S, et al. Nat Med. 2020 Jan;26(1):39-46. doi: 10.1038/s41591-019-0694-x. Epub 2019 Dec 23. Nat Med. 2020. PMID: 31873309 Free PMC article.
Myeloid cell-targeted therapies for solid tumours.
Goswami S, Anandhan S, Raychaudhuri D, Sharma P. Goswami S, et al. Nat Rev Immunol. 2023 Feb;23(2):106-120. doi: 10.1038/s41577-022-00737-w. Epub 2022 Jun 13. Nat Rev Immunol. 2023. PMID: 35697799 Review.
TSG-6+ cancer-associated fibroblasts modulate myeloid cell responses and impair anti-tumor response to immune checkpoint therapy in pancreatic cancer.
Anandhan S, Herbrich S, Goswami S, Guan B, Chen Y, Macaluso MD, Jindal S, Natarajan SM, Andrewes SW, Xiong L, Nagarajan A, Basu S, Tang DN, Liu J, Min J, Maitra A, Sharma P. Anandhan S, et al. Among authors: goswami s. Nat Commun. 2024 Jul 10;15(1):5291. doi: 10.1038/s41467-024-49189-x. Nat Commun. 2024. PMID: 38987547 Free PMC article.
Neoadjuvant PD-L1 plus CTLA-4 blockade in patients with cisplatin-ineligible operable high-risk urothelial carcinoma.
Gao J, Navai N, Alhalabi O, Siefker-Radtke A, Campbell MT, Tidwell RS, Guo CC, Kamat AM, Matin SF, Araujo JC, Shah AY, Msaouel P, Corn P, Wang J, Papadopoulos JN, Yadav SS, Blando JM, Duan F, Basu S, Liu W, Shen Y, Zhang Y, Macaluso MD, Wang Y, Chen J, Zhang J, Futreal A, Dinney C, Allison JP, Goswami S, Sharma P. Gao J, et al. Among authors: goswami s. Nat Med. 2020 Dec;26(12):1845-1851. doi: 10.1038/s41591-020-1086-y. Epub 2020 Oct 12. Nat Med. 2020. PMID: 33046869 Free PMC article. Clinical Trial.
1,419 results