Finucane O - Search Results

1

Inhibiting the NLRP3 inflammasome with MCC950 promotes non-phlogistic clearance of amyloid-β and cognitive function in APP/PS1 mice.

Dempsey C, Rubio Araiz A, Bryson KJ, Finucane O, Larkin C, Mills EL, Robertson AAB, Cooper MA, O'Neill LAJ, Lynch MA. Dempsey C, et al. Among authors: finucane o. Brain Behav Immun. 2017 Mar;61:306-316. doi: 10.1016/j.bbi.2016.12.014. Epub 2016 Dec 18. Brain Behav Immun. 2017. PMID: 28003153

2

Inflammatory microglia are glycolytic and iron retentive and typify the microglia in APP/PS1 mice.

Holland R, McIntosh AL, Finucane OM, Mela V, Rubio-Araiz A, Timmons G, McCarthy SA, Gun'ko YK, Lynch MA. Holland R, et al. Among authors: finucane om. Brain Behav Immun. 2018 Feb;68:183-196. doi: 10.1016/j.bbi.2017.10.017. Epub 2017 Oct 20. Brain Behav Immun. 2018. PMID: 29061364

3

The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1β-dependent manner in macrophages.

Finucane OM, Sugrue J, Rubio-Araiz A, Guillot-Sestier MV, Lynch MA. Finucane OM, et al. Sci Rep. 2019 Mar 11;9(1):4034. doi: 10.1038/s41598-019-40619-1. Sci Rep. 2019. PMID: 30858427 Free PMC article.

4

FTY720 Attenuates Infection-Induced Enhancement of Aβ Accumulation in APP/PS1 Mice by Modulating Astrocytic Activation.

McManus RM, Finucane OM, Wilk MM, Mills KHG, Lynch MA. McManus RM, et al. Among authors: finucane om. J Neuroimmune Pharmacol. 2017 Dec;12(4):670-681. doi: 10.1007/s11481-017-9753-6. Epub 2017 Jun 15. J Neuroimmune Pharmacol. 2017. PMID: 28620801

5

Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of β-amyloid.

Rubio-Araiz A, Finucane OM, Keogh S, Lynch MA. Rubio-Araiz A, et al. Among authors: finucane om. J Neuroinflammation. 2018 Aug 31;15(1):247. doi: 10.1186/s12974-018-1281-7. J Neuroinflammation. 2018. PMID: 30170611 Free PMC article.

6

Monounsaturated fatty acid-enriched high-fat diets impede adipose NLRP3 inflammasome-mediated IL-1β secretion and insulin resistance despite obesity.

Finucane OM, Lyons CL, Murphy AM, Reynolds CM, Klinger R, Healy NP, Cooke AA, Coll RC, McAllan L, Nilaweera KN, O'Reilly ME, Tierney AC, Morine MJ, Alcala-Diaz JF, Lopez-Miranda J, O'Connor DP, O'Neill LA, McGillicuddy FC, Roche HM. Finucane OM, et al. Diabetes. 2015 Jun;64(6):2116-28. doi: 10.2337/db14-1098. Epub 2015 Jan 27. Diabetes. 2015. PMID: 25626736

7

A casein hydrolysate protects mice against high fat diet induced hyperglycemia by attenuating NLRP3 inflammasome-mediated inflammation and improving insulin signaling.

Healy NP, Kirwan AM, McArdle MA, Holohan K, Nongonierma AB, Keane D, Kelly S, Celkova L, Lyons CL, McGillicuddy FC, Finucane OM, Murray BA, Kelly PM, Brennan L, FitzGerald RJ, Roche HM. Healy NP, et al. Among authors: finucane om. Mol Nutr Food Res. 2016 Nov;60(11):2421-2432. doi: 10.1002/mnfr.201501054. Epub 2016 Sep 8. Mol Nutr Food Res. 2016. PMID: 27390025

8

Dietary saturated fatty acids prime the NLRP3 inflammasome via TLR4 in dendritic cells-implications for diet-induced insulin resistance.

Reynolds CM, McGillicuddy FC, Harford KA, Finucane OM, Mills KH, Roche HM. Reynolds CM, et al. Mol Nutr Food Res. 2012 Aug;56(8):1212-22. doi: 10.1002/mnfr.201200058. Epub 2012 Jun 15. Mol Nutr Food Res. 2012. PMID: 22700321

9

Interactions between differential fatty acids and inflammatory stressors-impact on metabolic health.

Murphy AM, Lyons CL, Finucane OM, Roche HM. Murphy AM, et al. Prostaglandins Leukot Essent Fatty Acids. 2015 Jan;92:49-55. doi: 10.1016/j.plefa.2014.05.003. Epub 2014 Jun 3. Prostaglandins Leukot Essent Fatty Acids. 2015. PMID: 24947613 Review.

10

Macrophage migration inhibitory factor deficiency ameliorates high-fat diet induced insulin resistance in mice with reduced adipose inflammation and hepatic steatosis.

Finucane OM, Reynolds CM, McGillicuddy FC, Harford KA, Morrison M, Baugh J, Roche HM. Finucane OM, et al. PLoS One. 2014 Nov 20;9(11):e113369. doi: 10.1371/journal.pone.0113369. eCollection 2014. PLoS One. 2014. PMID: 25412423 Free PMC article.

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