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Impact of Memory T Cells on SARS-COV-2 Vaccine Response in Hematopoietic Stem Cell Transplant.
VanOudenhove J, Liu Y, Nelakanti R, Kim D, Busarello E, Ovalle NT, Qi Z, Mamillapalli P, Siddon A, Bai Z, Axtmayer A, Corso C, Kothari S, Foss F, Isufi I, Tebaldi T, Gowda L, Fan R, Seropian S, Halene S. VanOudenhove J, et al. Among authors: halene s. bioRxiv [Preprint]. 2023 Oct 27:2023.10.26.564259. doi: 10.1101/2023.10.26.564259. bioRxiv. 2023. PMID: 37961434 Free PMC article. Preprint.
A multicenter phase Ib trial of the histone deacetylase inhibitor entinostat in combination with pembrolizumab in patients with myelodysplastic syndromes/neoplasms or acute myeloid leukemia refractory to hypomethylating agents.
Bewersdorf JP, Shallis RM, Sharon E, Park S, Ramaswamy R, Roe CE, Irish JM, Caldwell A, Wei W, Yacoub A, Madanat YF, Zeidner JF, Altman JK, Odenike O, Yerrabothala S, Kovacsovics T, Podoltsev NA, Halene S, Little RF, Piekarz R, Gore SD, Kim TK, Zeidan AM. Bewersdorf JP, et al. Among authors: halene s. Ann Hematol. 2024 Jan;103(1):105-116. doi: 10.1007/s00277-023-05552-4. Epub 2023 Dec 1. Ann Hematol. 2024. PMID: 38036712 Clinical Trial.
SRF is required for neutrophil migration in response to inflammation.
Taylor A, Tang W, Bruscia EM, Zhang PX, Lin A, Gaines P, Wu D, Halene S. Taylor A, et al. Among authors: halene s. Blood. 2014 May 8;123(19):3027-36. doi: 10.1182/blood-2013-06-507582. Epub 2014 Feb 26. Blood. 2014. PMID: 24574460 Free PMC article.
A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies.
Song Y, Rongvaux A, Taylor A, Jiang T, Tebaldi T, Balasubramanian K, Bagale A, Terzi YK, Gbyli R, Wang X, Fu X, Gao Y, Zhao J, Podoltsev N, Xu M, Neparidze N, Wong E, Torres R, Bruscia EM, Kluger Y, Manz MG, Flavell RA, Halene S. Song Y, et al. Among authors: halene s. Nat Commun. 2019 Jan 21;10(1):366. doi: 10.1038/s41467-018-08166-x. Nat Commun. 2019. PMID: 30664659 Free PMC article.
A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options.
Sefik E, Israelow B, Zhao J, Qu R, Song E, Mirza H, Kaffe E, Halene S, Meffre E, Kluger Y, Nussenzweig M, Wilen CB, Iwasaki A, Flavell RA. Sefik E, et al. Among authors: halene s. Res Sq [Preprint]. 2021 Mar 17:rs.3.rs-279341. doi: 10.21203/rs.3.rs-279341/v1. Res Sq. 2021. Update in: Nat Biotechnol. 2022 Jun;40(6):906-920. doi: 10.1038/s41587-021-01155-4 PMID: 33758831 Free PMC article. Updated. Preprint.
112 results