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Page 1
First-in-class inhibitor of the T cell receptor for the treatment of autoimmune diseases.
Borroto A, Reyes-Garau D, Jiménez MA, Carrasco E, Moreno B, Martínez-Pasamar S, Cortés JR, Perona A, Abia D, Blanco S, Fuentes M, Arellano I, Lobo J, Heidarieh H, Rueda J, Esteve P, Cibrián D, Martinez-Riaño A, Mendoza P, Prieto C, Calleja E, Oeste CL, Orfao A, Fresno M, Sánchez-Madrid F, Alcamí A, Bovolenta P, Martín P, Villoslada P, Morreale A, Messeguer A, Alarcon B. Borroto A, et al. Sci Transl Med. 2016 Dec 21;8(370):370ra184. doi: 10.1126/scitranslmed.aaf2140. Sci Transl Med. 2016. PMID: 28003549
Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses.
Cruz-Adalia A, Ramirez-Santiago G, Osuna-Pérez J, Torres-Torresano M, Zorita V, Martínez-Riaño A, Boccasavia V, Borroto A, Martínez Del Hoyo G, González-Granado JM, Alarcón B, Sánchez-Madrid F, Veiga E. Cruz-Adalia A, et al. Nat Commun. 2017 Nov 17;8(1):1591. doi: 10.1038/s41467-017-01661-7. Nat Commun. 2017. PMID: 29147022 Free PMC article.
Author Correction: Conventional CD4+ T cells present bacterial antigens to induce cytotoxic and memory CD8+ T cell responses.
Cruz-Adalia A, Ramirez-Santiago G, Osuna-Pérez J, Torres-Torresano M, Zorita V, Martínez-Riaño A, Boccasavia V, Borroto A, Martínez Del Hoyo G, González-Granado JM, Alarcón B, Sánchez-Madrid F, Veiga E. Cruz-Adalia A, et al. Among authors: martinez riano a. Nat Commun. 2018 Jan 31;9(1):495. doi: 10.1038/s41467-018-03074-6. Nat Commun. 2018. PMID: 29386506 Free PMC article.
Antigen phagocytosis by B cells is required for a potent humoral response.
Martínez-Riaño A, Bovolenta ER, Mendoza P, Oeste CL, Martín-Bermejo MJ, Bovolenta P, Turner M, Martínez-Martín N, Alarcón B. Martínez-Riaño A, et al. EMBO Rep. 2018 Sep;19(9):e46016. doi: 10.15252/embr.201846016. Epub 2018 Jul 9. EMBO Rep. 2018. PMID: 29987136 Free PMC article.
13 results