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Page 1
Anti-ADAMTS13 autoantibodies in immune-mediated thrombotic thrombocytopenic purpura do not hamper ELISA-based quantification of ADAMTS13 antigen.
Dekimpe C, Roose E, Tersteeg C, Joly BS, Dewaele A, Horta S, Pareyn I, Vandenbulcke A, Deckmyn H, Feys HB, Tellier E, Kaplanski G, Scully M, Coppo P, De Meyer SF, Veyradier A, Vanhoorelbeke K. Dekimpe C, et al. J Thromb Haemost. 2020 Apr;18(4):985-990. doi: 10.1111/jth.14747. Epub 2020 Feb 27. J Thromb Haemost. 2020. PMID: 31989742 Free article.
Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura.
Roose E, Schelpe AS, Tellier E, Sinkovits G, Joly BS, Dekimpe C, Kaplanski G, Le Besnerais M, Mancini I, Falter T, Von Auer C, Feys HB, Reti M, Rossmann H, Vandenbulcke A, Pareyn I, Voorberg J, Greinacher A, Benhamou Y, Deckmyn H, Fijnheer R, Prohászka Z, Peyvandi F, Lämmle B, Coppo P, De Meyer SF, Veyradier A, Vanhoorelbeke K. Roose E, et al. Among authors: dekimpe c. Blood. 2020 Jul 16;136(3):353-361. doi: 10.1182/blood.2019004221. Blood. 2020. PMID: 32356859 Free article. Clinical Trial.
Co(III)-NTA Mediated Antigen Immobilization on a Fiber Optic-SPR Biosensor for Detection of Autoantibodies in Autoimmune Diseases: Application in Immune-Mediated Thrombotic Thrombocytopenic Purpura.
Horta S, Qu JH, Dekimpe C, Bonnez Q, Vandenbulcke A, Tellier E, Kaplanski G, Delport F, Geukens N, Lammertyn J, Vanhoorelbeke K. Horta S, et al. Among authors: dekimpe c. Anal Chem. 2020 Oct 20;92(20):13880-13887. doi: 10.1021/acs.analchem.0c02586. Epub 2020 Sep 29. Anal Chem. 2020. PMID: 32929962
Imbalance of von Willebrand factor and ADAMTS13 axis is rather a biomarker of strong inflammation and endothelial damage than a cause of thrombotic process in critically ill COVID-19 patients.
Joly BS, Darmon M, Dekimpe C, Dupont T, Dumas G, Yvin E, Beranger N, Vanhoorelbeke K, Azoulay E, Veyradier A. Joly BS, et al. Among authors: dekimpe c. J Thromb Haemost. 2021 Sep;19(9):2193-2198. doi: 10.1111/jth.15445. Epub 2021 Jul 27. J Thromb Haemost. 2021. PMID: 34219357 Free PMC article.
Plasma and rhADAMTS13 reduce trauma-induced organ failure by restoring the ADAMTS13-VWF axis.
Kleinveld DJB, Simons DDG, Dekimpe C, Deconinck SJ, Sloos PH, Maas MAW, Kers J, Muia J, Brohi K, Voorberg J, Vanhoorelbeke K, Hollmann MW, Juffermans NP; BloodNet. Kleinveld DJB, et al. Among authors: dekimpe c. Blood Adv. 2021 Sep 14;5(17):3478-3491. doi: 10.1182/bloodadvances.2021004404. Blood Adv. 2021. PMID: 34505883 Free PMC article.
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