Jaffee BD - Search Results

1

The effect of immunomodulating drugs on adjuvant-induced arthritis in Lewis rats.

Jaffee BD, Kerr JS, Jones EA, Giannaras JV, McGowan M, Ackerman NR. Jaffee BD, et al. Agents Actions. 1989 Jun;27(3-4):344-6. doi: 10.1007/BF01972818. Agents Actions. 1989. PMID: 2801321

2

The unique immunosuppressive activity of brequinar sodium.

Jaffee BD, Jones EA, Loveless SE, Chen SF. Jaffee BD, et al. Transplant Proc. 1993 Jun;25(3 Suppl 2):19-22. Transplant Proc. 1993. PMID: 7685954 No abstract available.

3

Brequinar sodium: inhibition of dihydroorotic acid dehydrogenase, depletion of pyrimidine pools, and consequent inhibition of immune functions in vitro.

Simon P, Townsend RM, Harris RR, Jones EA, Jaffee BD. Simon P, et al. Among authors: jaffee bd. Transplant Proc. 1993 Jun;25(3 Suppl 2):77-80. Transplant Proc. 1993. PMID: 8390742 No abstract available.

4

Effects of brequinar sodium on cynomolgus monkeys: immunosuppression and pharmacokinetics.

Jaffee BD, Jones EA, Zajac I, Magolda RL, Cramer DV, Makowka L. Jaffee BD, et al. Transplant Proc. 1993 Feb;25(1 Pt 1):710-1. Transplant Proc. 1993. PMID: 8438449 No abstract available.

5

Antiinflammatory 4,5-diarylpyrroles: synthesis and QSAR.

Wilkerson WW, Galbraith W, Gans-Brangs K, Grubb M, Hewes WE, Jaffee B, Kenney JP, Kerr J, Wong N. Wilkerson WW, et al. J Med Chem. 1994 Apr 1;37(7):988-98. doi: 10.1021/jm00033a017. J Med Chem. 1994. PMID: 8151626

6

The effect of a new immunosuppressive drug, brequinar sodium, on heart, liver, and kidney allograft rejection in the rat.

Cramer DV, Chapman FA, Jaffee BD, Jones EA, Knoop M, Hreha-Eiras G, Makowka L. Cramer DV, et al. Among authors: jaffee bd. Transplantation. 1992 Feb;53(2):303-8. doi: 10.1097/00007890-199202010-00009. Transplantation. 1992. PMID: 1531394

7

Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergy.

DeSilva DR, Jones EA, Favata MF, Jaffee BD, Magolda RL, Trzaskos JM, Scherle PA. DeSilva DR, et al. Among authors: jaffee bd. J Immunol. 1998 May 1;160(9):4175-81. J Immunol. 1998. PMID: 9574517

8

Heteroatom- and carbon-linked biphenyl analogs of Brequinar as immunosuppressive agents.

Batt DG, Petraitis JJ, Sherk SR, Copeland RA, Dowling RL, Taylor TL, Jones EA, Magolda RL, Jaffee BD. Batt DG, et al. Among authors: jaffee bd. Bioorg Med Chem Lett. 1998 Jul 7;8(13):1745-50. doi: 10.1016/s0960-894x(98)00308-4. Bioorg Med Chem Lett. 1998. PMID: 9873427

9

Inhibition of the pyrimidine biosynthetic pathway with S-8660, an analogue of brequinar sodium, prolongs cardiac allograft survival in rats.

Cramer DV, Chapman FA, Jaffee B, Jones EA, Makowka L. Cramer DV, et al. J Heart Lung Transplant. 1993 Jan-Feb;12(1 Pt 1):140-6. J Heart Lung Transplant. 1993. PMID: 8443191

10

Structure-activity relationships (SAR) of some tetracyclic heterocycles related to the immunosuppressive agent Brequinar Sodium.

Pitts WJ, Jetter JW, Pinto DJ, Orwat MJ, Batt DG, Sherk SR, Petraitis JJ, Jacobson IC, Copeland RA, Dowling RL, Jaffee BD, Gardner TL, Jones EA, Magolda RL. Pitts WJ, et al. Among authors: jaffee bd. Bioorg Med Chem Lett. 1998 Feb 3;8(3):307-12. doi: 10.1016/s0960-894x(98)00010-9. Bioorg Med Chem Lett. 1998. PMID: 9871675

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