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IRF4 and BATF are critical for CD8⁺ T-cell function following infection with LCMV.
Grusdat M, McIlwain DR, Xu HC, Pozdeev VI, Knievel J, Crome SQ, Robert-Tissot C, Dress RJ, Pandyra AA, Speiser DE, Lang E, Maney SK, Elford AR, Hamilton SR, Scheu S, Pfeffer K, Bode J, Mittrücker HW, Lohoff M, Huber M, Häussinger D, Ohashi PS, Mak TW, Lang KS, Lang PA. Grusdat M, et al. Among authors: xu hc. Cell Death Differ. 2014 Jul;21(7):1050-60. doi: 10.1038/cdd.2014.19. Epub 2014 Feb 14. Cell Death Differ. 2014. PMID: 24531538 Free PMC article.
Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity.
Xu HC, Grusdat M, Pandyra AA, Polz R, Huang J, Sharma P, Deenen R, Köhrer K, Rahbar R, Diefenbach A, Gibbert K, Löhning M, Höcker L, Waibler Z, Häussinger D, Mak TW, Ohashi PS, Lang KS, Lang PA. Xu HC, et al. Immunity. 2014 Jun 19;40(6):949-60. doi: 10.1016/j.immuni.2014.05.004. Epub 2014 Jun 5. Immunity. 2014. PMID: 24909887 Free article.
Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection.
Lang PA, Meryk A, Pandyra AA, Brenner D, Brüstle A, Xu HC, Merches K, Lang F, Khairnar V, Sharma P, Funkner P, Recher M, Shaabani N, Duncan GS, Duhan V, Homey B, Ohashi PS, Häussinger D, Knolle PA, Honke N, Mak TW, Lang KS. Lang PA, et al. Among authors: xu hc. Cell Death Differ. 2015 Jan;22(1):164-73. doi: 10.1038/cdd.2014.138. Epub 2014 Sep 26. Cell Death Differ. 2015. PMID: 25257173 Free PMC article.
T-cell STAT3 is required for the maintenance of humoral immunity to LCMV.
McIlwain DR, Grusdat M, Pozdeev VI, Xu HC, Shinde P, Reardon C, Hao Z, Beyer M, Bergthaler A, Häussinger D, Nolan GP, Lang KS, Lang PA. McIlwain DR, et al. Among authors: xu hc. Eur J Immunol. 2015 Feb;45(2):418-27. doi: 10.1002/eji.201445060. Epub 2014 Dec 15. Eur J Immunol. 2015. PMID: 25393615 Free PMC article.
Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection.
Xu HC, Huang J, Khairnar V, Duhan V, Pandyra AA, Grusdat M, Shinde P, McIlwain DR, Maney SK, Gommerman J, Löhning M, Ohashi PS, Mak TW, Pieper K, Sic H, Speletas M, Eibel H, Ware CF, Tumanov AV, Kruglov AA, Nedospasov SA, Häussinger D, Recher M, Lang KS, Lang PA. Xu HC, et al. J Virol. 2015 May;89(9):4748-59. doi: 10.1128/JVI.02976-14. Epub 2015 Feb 11. J Virol. 2015. PMID: 25673724 Free PMC article.
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production.
Khairnar V, Duhan V, Maney SK, Honke N, Shaabani N, Pandyra AA, Seifert M, Pozdeev V, Xu HC, Sharma P, Baldin F, Marquardsen F, Merches K, Lang E, Kirschning C, Westendorf AM, Häussinger D, Lang F, Dittmer U, Küppers R, Recher M, Hardt C, Scheffrahn I, Beauchemin N, Göthert JR, Singer BB, Lang PA, Lang KS. Khairnar V, et al. Among authors: xu hc. Nat Commun. 2015 Feb 18;6:6217. doi: 10.1038/ncomms7217. Nat Commun. 2015. PMID: 25692415 Free PMC article.
Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage.
Bhattacharya A, Hegazy AN, Deigendesch N, Kosack L, Cupovic J, Kandasamy RK, Hildebrandt A, Merkler D, Kühl AA, Vilagos B, Schliehe C, Panse I, Khamina K, Baazim H, Arnold I, Flatz L, Xu HC, Lang PA, Aderem A, Takaoka A, Superti-Furga G, Colinge J, Ludewig B, Löhning M, Bergthaler A. Bhattacharya A, et al. Among authors: xu hc. Immunity. 2015 Nov 17;43(5):974-86. doi: 10.1016/j.immuni.2015.10.013. Immunity. 2015. PMID: 26588782 Free PMC article.
240 results