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Page 1
Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation.
De Smet F, Saiz Rubio M, Hompes D, Naus E, De Baets G, Langenberg T, Hipp MS, Houben B, Claes F, Charbonneau S, Delgado Blanco J, Plaisance S, Ramkissoon S, Ramkissoon L, Simons C, van den Brandt P, Weijenberg M, Van England M, Lambrechts S, Amant F, D'Hoore A, Ligon KL, Sagaert X, Schymkowitz J, Rousseau F. De Smet F, et al. Among authors: de baets g. J Pathol. 2017 May;242(1):24-38. doi: 10.1002/path.4872. Epub 2017 Mar 23. J Pathol. 2017. PMID: 28035683
Role of neural guidance signals in blood vessel navigation.
Autiero M, De Smet F, Claes F, Carmeliet P. Autiero M, et al. Among authors: de smet f. Cardiovasc Res. 2005 Feb 15;65(3):629-38. doi: 10.1016/j.cardiores.2004.09.013. Cardiovasc Res. 2005. PMID: 15664389 Review.
Gain of function of mutant p53 by coaggregation with multiple tumor suppressors.
Xu J, Reumers J, Couceiro JR, De Smet F, Gallardo R, Rudyak S, Cornelis A, Rozenski J, Zwolinska A, Marine JC, Lambrechts D, Suh YA, Rousseau F, Schymkowitz J. Xu J, et al. Among authors: de smet f. Nat Chem Biol. 2011 May;7(5):285-95. doi: 10.1038/nchembio.546. Epub 2011 Mar 27. Nat Chem Biol. 2011. PMID: 21445056
Sequence-dependent internalization of aggregating peptides.
Couceiro JR, Gallardo R, De Smet F, De Baets G, Baatsen P, Annaert W, Roose K, Saelens X, Schymkowitz J, Rousseau F. Couceiro JR, et al. Among authors: de smet f, de baets g. J Biol Chem. 2015 Jan 2;290(1):242-58. doi: 10.1074/jbc.M114.586636. Epub 2014 Nov 12. J Biol Chem. 2015. PMID: 25391649 Free PMC article.
Structural hot spots for the solubility of globular proteins.
Ganesan A, Siekierska A, Beerten J, Brams M, Van Durme J, De Baets G, Van der Kant R, Gallardo R, Ramakers M, Langenberg T, Wilkinson H, De Smet F, Ulens C, Rousseau F, Schymkowitz J. Ganesan A, et al. Among authors: de smet f, de baets g. Nat Commun. 2016 Feb 24;7:10816. doi: 10.1038/ncomms10816. Nat Commun. 2016. PMID: 26905391 Free PMC article.
Sequence-Specific Protein Aggregation Generates Defined Protein Knockdowns in Plants.
Betti C, Vanhoutte I, Coutuer S, De Rycke R, Mishev K, Vuylsteke M, Aesaert S, Rombaut D, Gallardo R, De Smet F, Xu J, Van Lijsebettens M, Van Breusegem F, Inzé D, Rousseau F, Schymkowitz J, Russinova E. Betti C, et al. Among authors: de rycke r, de smet f. Plant Physiol. 2016 Jun;171(2):773-87. doi: 10.1104/pp.16.00335. Epub 2016 May 4. Plant Physiol. 2016. PMID: 27208282 Free PMC article.
De novo design of a biologically active amyloid.
Gallardo R, Ramakers M, De Smet F, Claes F, Khodaparast L, Khodaparast L, Couceiro JR, Langenberg T, Siemons M, Nyström S, Young LJ, Laine RF, Young L, Radaelli E, Benilova I, Kumar M, Staes A, Desager M, Beerens M, Vandervoort P, Luttun A, Gevaert K, Bormans G, Dewerchin M, Van Eldere J, Carmeliet P, Vande Velde G, Verfaillie C, Kaminski CF, De Strooper B, Hammarström P, Nilsson KP, Serpell L, Schymkowitz J, Rousseau F. Gallardo R, et al. Among authors: de strooper b, de smet f. Science. 2016 Nov 11;354(6313):aah4949. doi: 10.1126/science.aah4949. Science. 2016. PMID: 27846578 Free article.
Linking single-cell measurements of mass, growth rate, and gene expression.
Kimmerling RJ, Prakadan SM, Gupta AJ, Calistri NL, Stevens MM, Olcum S, Cermak N, Drake RS, Pelton K, De Smet F, Ligon KL, Shalek AK, Manalis SR. Kimmerling RJ, et al. Among authors: de smet f. Genome Biol. 2018 Nov 27;19(1):207. doi: 10.1186/s13059-018-1576-0. Genome Biol. 2018. PMID: 30482222 Free PMC article.
Generation of patient-derived models from a metastatic pediatric diffuse leptomeningeal glioneuronal tumor with KIAA1549::BRAF fusion.
Messiaen J, Claeys A, Shetty A, Spans L, Derweduwe M, Uyttebroeck A, Depreitere B, Vanden Bempt I, Sciot R, Ligon KL, Jones DTW, Jacobs SA, De Smet F. Messiaen J, et al. Among authors: de smet f. Acta Neuropathol. 2022 Oct;144(4):793-797. doi: 10.1007/s00401-022-02473-w. Epub 2022 Aug 4. Acta Neuropathol. 2022. PMID: 35925403 Free PMC article. No abstract available.
147 results