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Malignant Astrocytic Tumor Progression Potentiated by JAK-mediated Recruitment of Myeloid Cells.
Rajappa P, Cobb WS, Vartanian E, Huang Y, Daly L, Hoffman C, Zhang J, Shen B, Yanowitch R, Garg K, Cisse B, Haddock S, Huse J, Pisapia DJ, Chan TA, Lyden DC, Bromberg JF, Greenfield JP. Rajappa P, et al. Among authors: lyden dc. Clin Cancer Res. 2017 Jun 15;23(12):3109-3119. doi: 10.1158/1078-0432.CCR-16-1508. Epub 2016 Dec 30. Clin Cancer Res. 2017. PMID: 28039266 Free PMC article.
Preparing the "soil": the premetastatic niche.
Kaplan RN, Rafii S, Lyden D. Kaplan RN, et al. Cancer Res. 2006 Dec 1;66(23):11089-93. doi: 10.1158/0008-5472.CAN-06-2407. Cancer Res. 2006. PMID: 17145848 Free PMC article. Review.
Inflammation joins the "niche".
Peinado H, Rafii S, Lyden D. Peinado H, et al. Cancer Cell. 2008 Nov 4;14(5):347-9. doi: 10.1016/j.ccr.2008.10.012. Cancer Cell. 2008. PMID: 18977322 Free PMC article.
Stat3 mediates expression of autotaxin in breast cancer.
Azare J, Doane A, Leslie K, Chang Q, Berishaj M, Nnoli J, Mark K, Al-Ahmadie H, Gerald W, Hassimi M, Viale A, Stracke M, Lyden D, Bromberg J. Azare J, et al. PLoS One. 2011;6(11):e27851. doi: 10.1371/journal.pone.0027851. Epub 2011 Nov 28. PLoS One. 2011. PMID: 22140473 Free PMC article.
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET.
Peinado H, Alečković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, García-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D. Peinado H, et al. Nat Med. 2012 Jun;18(6):883-91. doi: 10.1038/nm.2753. Nat Med. 2012. PMID: 22635005 Free PMC article.
STAT3 negatively regulates thyroid tumorigenesis.
Couto JP, Daly L, Almeida A, Knauf JA, Fagin JA, Sobrinho-Simões M, Lima J, Máximo V, Soares P, Lyden D, Bromberg JF. Couto JP, et al. Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):E2361-70. doi: 10.1073/pnas.1201232109. Epub 2012 Aug 13. Proc Natl Acad Sci U S A. 2012. PMID: 22891351 Free PMC article.
Molecular diagnostics in paediatric glial tumours.
Kim JH, Huse JT, Huang Y, Lyden D, Greenfield JP. Kim JH, et al. Lancet Oncol. 2013 Jan;14(1):e19-27. doi: 10.1016/S1470-2045(12)70577-6. Lancet Oncol. 2013. PMID: 23276367 Review.
151 results