Rosario S - Search Results

1

Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance.

Ku SY, Rosario S, Wang Y, Mu P, Seshadri M, Goodrich ZW, Goodrich MM, Labbé DP, Gomez EC, Wang J, Long HW, Xu B, Brown M, Loda M, Sawyers CL, Ellis L, Goodrich DW. Ku SY, et al. Among authors: rosario s. Science. 2017 Jan 6;355(6320):78-83. doi: 10.1126/science.aah4199. Science. 2017. PMID: 28059767 Free PMC article.

2

Mitochondrial protection impairs BET bromodomain inhibitor-mediated cell death and provides rationale for combination therapeutic strategies.

Lasorsa E, Smonksey M, Kirk JS, Rosario S, Hernandez-Ilizaliturri FJ, Ellis L. Lasorsa E, et al. Among authors: rosario s. Cell Death Dis. 2015 Dec 10;6(12):e2014. doi: 10.1038/cddis.2015.352. Cell Death Dis. 2015. PMID: 26658189 Free PMC article.

3

EZH2 inhibition re-sensitizes multidrug resistant B-cell lymphomas to etoposide mediated apoptosis.

Smonskey M, Lasorsa E, Rosario S, Kirk JS, Hernandez-Ilizaliturri FJ, Ellis L. Smonskey M, et al. Among authors: rosario s. Oncoscience. 2016 Jan 29;3(1):21-30. doi: 10.18632/oncoscience.288. eCollection 2016. Oncoscience. 2016. PMID: 26973857 Free PMC article.

4

TOP2A and EZH2 Provide Early Detection of an Aggressive Prostate Cancer Subgroup.

Labbé DP, Sweeney CJ, Brown M, Galbo P, Rosario S, Wadosky KM, Ku SY, Sjöström M, Alshalalfa M, Erho N, Davicioni E, Karnes RJ, Schaeffer EM, Jenkins RB, Den RB, Ross AE, Bowden M, Huang Y, Gray KP, Feng FY, Spratt DE, Goodrich DW, Eng KH, Ellis L. Labbé DP, et al. Among authors: rosario s. Clin Cancer Res. 2017 Nov 15;23(22):7072-7083. doi: 10.1158/1078-0432.CCR-17-0413. Epub 2017 Sep 12. Clin Cancer Res. 2017. PMID: 28899973 Free PMC article.

5

Pan-cancer molecular analysis of the RB tumor suppressor pathway.

Knudsen ES, Nambiar R, Rosario SR, Smiraglia DJ, Goodrich DW, Witkiewicz AK. Knudsen ES, et al. Among authors: rosario sr. Commun Biol. 2020 Apr 2;3(1):158. doi: 10.1038/s42003-020-0873-9. Commun Biol. 2020. PMID: 32242058 Free PMC article.

6

Hypoxic activation of PFKFB4 in breast tumor microenvironment shapes metabolic and cellular plasticity to accentuate metastatic competence.

Dai T, Rosario SR, Katsuta E, Sawant Dessai A, Paterson EJ, Novickis AT, Cortes Gomez E, Zhu B, Liu S, Wang H, Abrams SI, Seshadri M, Bshara W, Dasgupta S. Dai T, et al. Among authors: rosario sr. Cell Rep. 2022 Dec 6;41(10):111756. doi: 10.1016/j.celrep.2022.111756. Cell Rep. 2022. PMID: 36476868 Free PMC article.

7

Race-specific coregulatory and transcriptomic profiles associated with DNA methylation and androgen receptor in prostate cancer.

Ramakrishnan S, Cortes-Gomez E, Athans SR, Attwood KM, Rosario SR, Kim SJ, Mager DE, Isenhart EG, Hu Q, Wang J, Woloszynska A. Ramakrishnan S, et al. Among authors: rosario sr. Genome Med. 2024 Apr 2;16(1):52. doi: 10.1186/s13073-024-01323-6. Genome Med. 2024. PMID: 38566104 Free PMC article. Review.

8

Notch signaling suppresses neuroendocrine differentiation and alters the immune microenvironment in advanced prostate cancer.

Ku SY, Wang Y, Garcia MM, Yamada Y, Mizuno K, Long MD, Rosario S, Chinnam M, Al Assaad M, Puca L, Kim MJ, Bakht MK, Venkadakrishnan VB, Robinson BD, Acosta AM, Wadosky KM, Mosquera JM, Goodrich DW, Beltran H. Ku SY, et al. Among authors: rosario s. J Clin Invest. 2024 Jul 18;134(17):e175217. doi: 10.1172/JCI175217. J Clin Invest. 2024. PMID: 39024561 Free PMC article.

9

Integrative multi-omics analysis uncovers tumor-immune-gut axis influencing immunotherapy outcomes in ovarian cancer.

Rosario SR, Long MD, Chilakapati S, Gomez EC, Battaglia S, Singh PK, Wang J, Wang K, Attwood K, Hess SM, McGray AJR, Odunsi K, Segal BH, Paragh G, Liu S, Wargo JA, Zsiros E. Rosario SR, et al. Nat Commun. 2024 Dec 5;15(1):10609. doi: 10.1038/s41467-024-54565-8. Nat Commun. 2024. PMID: 39638782 Free PMC article. Clinical Trial.

10

The Challenges of Modeling Drug Resistance to Antiangiogenic Therapy.

Mastri M, Rosario S, Tracz A, Frink RE, Brekken RA, Ebos JM. Mastri M, et al. Among authors: rosario s. Curr Drug Targets. 2016;17(15):1747-1754. doi: 10.2174/1389450117666151209123544. Curr Drug Targets. 2016. PMID: 26648063 Free PMC article. Review.

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