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Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.
Szibor M, Dhandapani PK, Dufour E, Holmström KM, Zhuang Y, Salwig I, Wittig I, Heidler J, Gizatullina Z, Gainutdinov T; German Mouse Clinic Consortium; Fuchs H, Gailus-Durner V, de Angelis MH, Nandania J, Velagapudi V, Wietelmann A, Rustin P, Gellerich FN, Jacobs HT, Braun T. Szibor M, et al. Among authors: wittig i. Dis Model Mech. 2017 Feb 1;10(2):163-171. doi: 10.1242/dmm.027839. Epub 2016 Dec 14. Dis Model Mech. 2017. PMID: 28067626 Free PMC article.
MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.
Becker L, Kling E, Schiller E, Zeh R, Schrewe A, Hölter SM, Mossbrugger I, Calzada-Wack J, Strecker V, Wittig I, Dumitru I, Wenz T, Bender A, Aichler M, Janik D, Neff F, Walch A, Quintanilla-Fend L, Floss T, Bekeredjian R, Gailus-Durner V, Fuchs H, Wurst W, Meitinger T, Prokisch H, de Angelis MH, Klopstock T. Becker L, et al. Among authors: wittig i. PLoS One. 2014 Dec 15;9(12):e114918. doi: 10.1371/journal.pone.0114918. eCollection 2014. PLoS One. 2014. PMID: 25506927 Free PMC article.
Supercomplex-associated Cox26 protein binds to cytochrome c oxidase.
Strecker V, Kadeer Z, Heidler J, Cruciat CM, Angerer H, Giese H, Pfeiffer K, Stuart RA, Wittig I. Strecker V, et al. Among authors: wittig i. Biochim Biophys Acta. 2016 Jul;1863(7 Pt A):1643-52. doi: 10.1016/j.bbamcr.2016.04.012. Epub 2016 Apr 16. Biochim Biophys Acta. 2016. PMID: 27091403 Free PMC article.
Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle tissue.
Winter L, Wittig I, Peeva V, Eggers B, Heidler J, Chevessier F, Kley RA, Barkovits K, Strecker V, Berwanger C, Herrmann H, Marcus K, Kornblum C, Kunz WS, Schröder R, Clemen CS. Winter L, et al. Among authors: wittig i. Acta Neuropathol. 2016 Sep;132(3):453-73. doi: 10.1007/s00401-016-1592-7. Epub 2016 Jul 8. Acta Neuropathol. 2016. PMID: 27393313 Free PMC article.
Data file of a deep proteome analysis of the prefrontal cortex in aged mice with progranulin deficiency or neuronal overexpression of progranulin.
Heidler J, Hardt S, Wittig I, Tegeder I. Heidler J, et al. Among authors: wittig i. Data Brief. 2016 Nov 19;9:1070-1073. doi: 10.1016/j.dib.2016.11.030. eCollection 2016 Dec. Data Brief. 2016. PMID: 27921079 Free PMC article.
Zimmer, C. Moser, C. Behrends, F. Koentgen, I. Wittig, M.H. Schmidt, A.M. Clement, T. Deller, I. Tegeder, 2016) [1]....
Zimmer, C. Moser, C. Behrends, F. Koentgen, I. Wittig, M.H. Schmidt, A.M. Clement, T. Deller, I. Tegeder, 2016) [1]....
215 results