Fredman G - Search Results

1

MerTK receptor cleavage promotes plaque necrosis and defective resolution in atherosclerosis.

Cai B, Thorp EB, Doran AC, Sansbury BE, Daemen MJ, Dorweiler B, Spite M, Fredman G, Tabas I. Cai B, et al. Among authors: fredman g. J Clin Invest. 2017 Feb 1;127(2):564-568. doi: 10.1172/JCI90520. Epub 2017 Jan 9. J Clin Invest. 2017. PMID: 28067670 Free PMC article.

2

Recent advances in the role of immunity in atherosclerosis.

Fredman G, Spite M. Fredman G, et al. Circ Res. 2013 Dec 6;113(12):e111-4. doi: 10.1161/CIRCRESAHA.113.302986. Circ Res. 2013. PMID: 24311619 Review. No abstract available.

3

Common therapeutic targets in cardiometabolic disease.

Fredman G, Ozcan L, Tabas I. Fredman G, et al. Sci Transl Med. 2014 Jun 4;6(239):239ps5. doi: 10.1126/scitranslmed.3008908. Sci Transl Med. 2014. PMID: 24898746 Free PMC article. Review.

4

Inflammation and its resolution as determinants of acute coronary syndromes.

Libby P, Tabas I, Fredman G, Fisher EA. Libby P, et al. Among authors: fredman g. Circ Res. 2014 Jun 6;114(12):1867-79. doi: 10.1161/CIRCRESAHA.114.302699. Circ Res. 2014. PMID: 24902971 Free PMC article. Review.

5

Resolvin D1 limits 5-lipoxygenase nuclear localization and leukotriene B4 synthesis by inhibiting a calcium-activated kinase pathway.

Fredman G, Ozcan L, Spolitu S, Hellmann J, Spite M, Backs J, Tabas I. Fredman G, et al. Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14530-5. doi: 10.1073/pnas.1410851111. Epub 2014 Sep 22. Proc Natl Acad Sci U S A. 2014. PMID: 25246560 Free PMC article.

6

Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice.

Fredman G, Kamaly N, Spolitu S, Milton J, Ghorpade D, Chiasson R, Kuriakose G, Perretti M, Farokzhad O, Tabas I. Fredman G, et al. Sci Transl Med. 2015 Feb 18;7(275):275ra20. doi: 10.1126/scitranslmed.aaa1065. Sci Transl Med. 2015. PMID: 25695999 Free PMC article.

7

Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis.

Kamaly N, Fredman G, Fojas JJ, Subramanian M, Choi WI, Zepeda K, Vilos C, Yu M, Gadde S, Wu J, Milton J, Carvalho Leitao R, Rosa Fernandes L, Hasan M, Gao H, Nguyen V, Harris J, Tabas I, Farokhzad OC. Kamaly N, et al. Among authors: fredman g. ACS Nano. 2016 May 24;10(5):5280-92. doi: 10.1021/acsnano.6b01114. Epub 2016 Apr 28. ACS Nano. 2016. PMID: 27100066 Free PMC article.

8

MerTK cleavage limits proresolving mediator biosynthesis and exacerbates tissue inflammation.

Cai B, Thorp EB, Doran AC, Subramanian M, Sansbury BE, Lin CS, Spite M, Fredman G, Tabas I. Cai B, et al. Among authors: fredman g. Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6526-31. doi: 10.1073/pnas.1524292113. Epub 2016 May 19. Proc Natl Acad Sci U S A. 2016. PMID: 27199481 Free PMC article.

9

An imbalance between specialized pro-resolving lipid mediators and pro-inflammatory leukotrienes promotes instability of atherosclerotic plaques.

Fredman G, Hellmann J, Proto JD, Kuriakose G, Colas RA, Dorweiler B, Connolly ES, Solomon R, Jones DM, Heyer EJ, Spite M, Tabas I. Fredman G, et al. Nat Commun. 2016 Sep 23;7:12859. doi: 10.1038/ncomms12859. Nat Commun. 2016. PMID: 27659679 Free PMC article.

10

Specialized pro-resolving mediators in cardiovascular diseases.

Fredman G, Spite M. Fredman G, et al. Mol Aspects Med. 2017 Dec;58:65-71. doi: 10.1016/j.mam.2017.02.003. Epub 2017 Feb 28. Mol Aspects Med. 2017. PMID: 28257820 Free PMC article. Review.

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