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Cu (I) catalyzed alkyne-azide 1,3-dipolar cycloaddition (CuAAC): Synthesis of 17α-[1-(substituted phenyl)-1,2,3-triazol-4-yl]-19-nor-testosterone-17β-yl acetates targeting progestational and antipro-liferative activities.
Mohamed ZH, El-Koussi NA, Mahfouz NM, Youssef AF, Abdel Jaleel GA, Shouman SA. Mohamed ZH, et al. Among authors: shouman sa. Eur J Med Chem. 2015 Jun 5;97:75-82. doi: 10.1016/j.ejmech.2015.04.045. Epub 2015 Apr 28. Eur J Med Chem. 2015. PMID: 25942354
Part I: Design, synthesis and biological evaluation of novel pyrazole-benzimidazole conjugates as checkpoint kinase 2 (Chk2) inhibitors with studying their activities alone and in combination with genotoxic drugs.
Galal SA, Abdelsamie AS, Shouman SA, Attia YM, Ali HI, Tabll A, El-Shenawy R, El Abd YS, Ali MM, Mahmoud AE, Abdel-Halim AH, Fyiad AA, Girgis AS, El-Diwani HI. Galal SA, et al. Among authors: shouman sa. Eur J Med Chem. 2017 Jul 7;134:392-405. doi: 10.1016/j.ejmech.2017.03.090. Epub 2017 Apr 14. Eur J Med Chem. 2017. PMID: 28433679
77 results