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Membrane-Depolarizing Channel Blockers Induce Selective Glioma Cell Death by Impairing Nutrient Transport and Unfolded Protein/Amino Acid Responses.
Niklasson M, Maddalo G, Sramkova Z, Mutlu E, Wee S, Sekyrova P, Schmidt L, Fritz N, Dehnisch I, Kyriatzis G, Krafcikova M, Carson BB, Feenstra JM, Marinescu VD, Segerman A, Haraldsson M, Gustavsson AL, Hammarström LG, Jenmalm Jensen A, Uhrbom L, Altelaar AF, Linnarsson S, Uhlén P, Trantirek L, Vincent CT, Nelander S, Enger PØ, Andäng M. Niklasson M, et al. Among authors: altelaar af. Cancer Res. 2017 Apr 1;77(7):1741-1752. doi: 10.1158/0008-5472.CAN-16-2274. Epub 2017 Jan 13. Cancer Res. 2017. PMID: 28087597
ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma.
Smit MA, Maddalo G, Greig K, Raaijmakers LM, Possik PA, van Breukelen B, Cappadona S, Heck AJ, Altelaar AF, Peeper DS. Smit MA, et al. Among authors: altelaar af. Mol Syst Biol. 2014 Dec 23;10(12):772. doi: 10.15252/msb.20145450. Mol Syst Biol. 2014. PMID: 25538140 Free PMC article.
Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK.
Vogel CJ, Smit MA, Maddalo G, Possik PA, Sparidans RW, van der Burg SH, Verdegaal EM, Heck AJ, Samatar AA, Beijnen JH, Altelaar AF, Peeper DS. Vogel CJ, et al. Among authors: altelaar af. Pigment Cell Melanoma Res. 2015 May;28(3):307-17. doi: 10.1111/pcmr.12364. Epub 2015 Apr 6. Pigment Cell Melanoma Res. 2015. PMID: 25728708
A System-wide Approach to Monitor Responses to Synergistic BRAF and EGFR Inhibition in Colorectal Cancer Cells.
Ressa A, Bosdriesz E, de Ligt J, Mainardi S, Maddalo G, Prahallad A, Jager M, de la Fonteijne L, Fitzpatrick M, Groten S, Altelaar AFM, Bernards R, Cuppen E, Wessels L, Heck AJR. Ressa A, et al. Among authors: altelaar afm. Mol Cell Proteomics. 2018 Oct;17(10):1892-1908. doi: 10.1074/mcp.RA117.000486. Epub 2018 Jul 3. Mol Cell Proteomics. 2018. PMID: 29970458 Free PMC article.
86 results