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Mice with hyperbilirubinemia due to Gilbert's syndrome polymorphism are resistant to hepatic steatosis by decreased serine 73 phosphorylation of PPARα.
Hinds TD Jr, Hosick PA, Chen S, Tukey RH, Hankins MW, Nestor-Kalinoski A, Stec DE. Hinds TD Jr, et al. Among authors: hosick pa. Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E244-E252. doi: 10.1152/ajpendo.00396.2016. Epub 2017 Jan 17. Am J Physiol Endocrinol Metab. 2017. PMID: 28096081 Free PMC article.
Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α.
Hinds TD Jr, Burns KA, Hosick PA, McBeth L, Nestor-Kalinoski A, Drummond HA, AlAmodi AA, Hankins MW, Vanden Heuvel JP, Stec DE. Hinds TD Jr, et al. Among authors: hosick pa. J Biol Chem. 2016 Nov 25;291(48):25179-25191. doi: 10.1074/jbc.M116.731703. Epub 2016 Oct 10. J Biol Chem. 2016. PMID: 27738106 Free PMC article.
Bilirubin, renal hemodynamics, and blood pressure.
Stec DE, Hosick PA, Granger JP. Stec DE, et al. Among authors: hosick pa. Front Pharmacol. 2012 Feb 14;3:18. doi: 10.3389/fphar.2012.00018. eCollection 2012. Front Pharmacol. 2012. PMID: 22347861 Free PMC article.
Biliverdin reductase isozymes in metabolism.
O'Brien L, Hosick PA, John K, Stec DE, Hinds TD Jr. O'Brien L, et al. Among authors: hosick pa. Trends Endocrinol Metab. 2015 Apr;26(4):212-20. doi: 10.1016/j.tem.2015.02.001. Epub 2015 Feb 25. Trends Endocrinol Metab. 2015. PMID: 25726384 Free PMC article. Review.
37 results