Ozawa Y - Search Results

1

Targeting of tumor growth and angiogenesis underlies the enhanced antitumor activity of lenvatinib in combination with everolimus.

Matsuki M, Adachi Y, Ozawa Y, Kimura T, Hoshi T, Okamoto K, Tohyama O, Mitsuhashi K, Yamaguchi A, Matsui J, Funahashi Y. Matsuki M, et al. Among authors: ozawa y. Cancer Sci. 2017 Apr;108(4):763-771. doi: 10.1111/cas.13169. Epub 2017 Apr 20. Cancer Sci. 2017. PMID: 28107584 Free PMC article.

2

An experimental model of bone metastasis by human lung cancer cells: the role of parathyroid hormone-related protein in bone metastasis.

Iguchi H, Tanaka S, Ozawa Y, Kashiwakuma T, Kimura T, Hiraga T, Ozawa H, Kono A. Iguchi H, et al. Among authors: ozawa y, ozawa h. Cancer Res. 1996 Sep 1;56(17):4040-3. Cancer Res. 1996. PMID: 8752176

3

Discovery of novel antitumor sulfonamides targeting G1 phase of the cell cycle.

Owa T, Yoshino H, Okauchi T, Yoshimatsu K, Ozawa Y, Sugi NH, Nagasu T, Koyanagi N, Kitoh K. Owa T, et al. Among authors: ozawa y. J Med Chem. 1999 Sep 23;42(19):3789-99. doi: 10.1021/jm9902638. J Med Chem. 1999. PMID: 10508428

4

E7070, a novel sulphonamide agent with potent antitumour activity in vitro and in vivo.

Ozawa Y, Sugi NH, Nagasu T, Owa T, Watanabe T, Koyanagi N, Yoshino H, Kitoh K, Yoshimatsu K. Ozawa Y, et al. Eur J Cancer. 2001 Nov;37(17):2275-82. doi: 10.1016/s0959-8049(01)00275-1. Eur J Cancer. 2001. PMID: 11677118

5

Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium.

Funahashi Y, Sugi NH, Semba T, Yamamoto Y, Hamaoka S, Tsukahara-Tamai N, Ozawa Y, Tsuruoka A, Nara K, Takahashi K, Okabe T, Kamata J, Owa T, Ueda N, Haneda T, Yonaga M, Yoshimatsu K, Wakabayashi T. Funahashi Y, et al. Among authors: ozawa y. Cancer Res. 2002 Nov 1;62(21):6116-23. Cancer Res. 2002. PMID: 12414636

6

Microregional antitumor activity of a small-molecule hypoxia-inducible factor 1 inhibitor.

Okamoto K, Ito D, Miyazaki K, Watanabe S, Tohyama O, Yokoi A, Ozawa Y, Asano M, Kawamura T, Yamane Y, Nagao S, Funasaka S, Kamata J, Kotake Y, Aoki M, Tsukahara N, Mizui Y, Tanaka I, Sawada K. Okamoto K, et al. Among authors: ozawa y. Int J Mol Med. 2012 Apr;29(4):541-9. doi: 10.3892/ijmm.2011.875. Epub 2011 Dec 29. Int J Mol Med. 2012. PMID: 22211243 Free PMC article.

7

Therapeutic potential and molecular mechanism of a novel sulfonamide anticancer drug, indisulam (E7070) in combination with CPT-11 for cancer treatment.

Ozawa Y, Kusano K, Owa T, Yokoi A, Asada M, Yoshimatsu K. Ozawa Y, et al. Cancer Chemother Pharmacol. 2012 May;69(5):1353-62. doi: 10.1007/s00280-012-1844-8. Epub 2012 Feb 17. Cancer Chemother Pharmacol. 2012. PMID: 22349812

8

Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states.

Yoshida T, Ozawa Y, Kimura T, Sato Y, Kuznetsov G, Xu S, Uesugi M, Agoulnik S, Taylor N, Funahashi Y, Matsui J. Yoshida T, et al. Among authors: ozawa y. Br J Cancer. 2014 Mar 18;110(6):1497-505. doi: 10.1038/bjc.2014.80. Epub 2014 Feb 25. Br J Cancer. 2014. PMID: 24569463 Free PMC article.

9

Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models.

Funahashi Y, Okamoto K, Adachi Y, Semba T, Uesugi M, Ozawa Y, Tohyama O, Uehara T, Kimura T, Watanabe H, Asano M, Kawano S, Tizon X, McCracken PJ, Matsui J, Aoshima K, Nomoto K, Oda Y. Funahashi Y, et al. Among authors: ozawa y. Cancer Sci. 2014 Oct;105(10):1334-42. doi: 10.1111/cas.12488. Epub 2014 Sep 16. Cancer Sci. 2014. PMID: 25060424 Free PMC article.

10

Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors.

Nagao S, Yamane Y, Funasaka S, Tanaka K, Miyazaki K, Kotake Y, Kamata J, Watanabe-Miyano S, Toyama O, Ozawa Y, Mizui Y, Okamoto K, Ito D. Nagao S, et al. Among authors: ozawa y. Bioorg Med Chem. 2014 Oct 1;22(19):5513-29. doi: 10.1016/j.bmc.2014.07.020. Epub 2014 Jul 30. Bioorg Med Chem. 2014. PMID: 25139751

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