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Antibiotics induce redox-related physiological alterations as part of their lethality.
Dwyer DJ, Belenky PA, Yang JH, MacDonald IC, Martell JD, Takahashi N, Chan CT, Lobritz MA, Braff D, Schwarz EG, Ye JD, Pati M, Vercruysse M, Ralifo PS, Allison KR, Khalil AS, Ting AY, Walker GC, Collins JJ. Dwyer DJ, et al. Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2100-9. doi: 10.1073/pnas.1401876111. Epub 2014 May 6. Proc Natl Acad Sci U S A. 2014. PMID: 24803433 Free PMC article.
Antibiotic efficacy is linked to bacterial cellular respiration.
Lobritz MA, Belenky P, Porter CB, Gutierrez A, Yang JH, Schwarz EG, Dwyer DJ, Khalil AS, Collins JJ. Lobritz MA, et al. Among authors: belenky p. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8173-80. doi: 10.1073/pnas.1509743112. Epub 2015 Jun 22. Proc Natl Acad Sci U S A. 2015. PMID: 26100898 Free PMC article.
A role for the bacterial GATC methylome in antibiotic stress survival.
Cohen NR, Ross CA, Jain S, Shapiro RS, Gutierrez A, Belenky P, Li H, Collins JJ. Cohen NR, et al. Among authors: belenky p. Nat Genet. 2016 May;48(5):581-6. doi: 10.1038/ng.3530. Epub 2016 Mar 21. Nat Genet. 2016. PMID: 26998690 Free PMC article.
52 results