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195 results

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Page 1
Quantifying the accretion of hyperphosphorylated tau in the locus coeruleus and dorsal raphe nucleus: the pathological building blocks of early Alzheimer's disease.
Ehrenberg AJ, Nguy AK, Theofilas P, Dunlop S, Suemoto CK, Di Lorenzo Alho AT, Leite RP, Diehl Rodriguez R, Mejia MB, Rüb U, Farfel JM, de Lucena Ferretti-Rebustini RE, Nascimento CF, Nitrini R, Pasquallucci CA, Jacob-Filho W, Miller B, Seeley WW, Heinsen H, Grinberg LT. Ehrenberg AJ, et al. Among authors: heinsen h. Neuropathol Appl Neurobiol. 2017 Aug;43(5):393-408. doi: 10.1111/nan.12387. Epub 2017 Mar 31. Neuropathol Appl Neurobiol. 2017. PMID: 28117917 Free PMC article.
Locus coeruleus volume and cell population changes during Alzheimer's disease progression: A stereological study in human postmortem brains with potential implication for early-stage biomarker discovery.
Theofilas P, Ehrenberg AJ, Dunlop S, Di Lorenzo Alho AT, Nguy A, Leite REP, Rodriguez RD, Mejia MB, Suemoto CK, Ferretti-Rebustini REL, Polichiso L, Nascimento CF, Seeley WW, Nitrini R, Pasqualucci CA, Jacob Filho W, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. Theofilas P, et al. Among authors: heinsen h. Alzheimers Dement. 2017 Mar;13(3):236-246. doi: 10.1016/j.jalz.2016.06.2362. Epub 2016 Aug 8. Alzheimers Dement. 2017. PMID: 27513978 Free PMC article.
Probing the correlation of neuronal loss, neurofibrillary tangles, and cell death markers across the Alzheimer's disease Braak stages: a quantitative study in humans.
Theofilas P, Ehrenberg AJ, Nguy A, Thackrey JM, Dunlop S, Mejia MB, Alho AT, Paraizo Leite RE, Rodriguez RD, Suemoto CK, Nascimento CF, Chin M, Medina-Cleghorn D, Cuervo AM, Arkin M, Seeley WW, Miller BL, Nitrini R, Pasqualucci CA, Filho WJ, Rueb U, Neuhaus J, Heinsen H, Grinberg LT. Theofilas P, et al. Among authors: heinsen h. Neurobiol Aging. 2018 Jan;61:1-12. doi: 10.1016/j.neurobiolaging.2017.09.007. Epub 2017 Sep 20. Neurobiol Aging. 2018. PMID: 29031088 Free PMC article.
Selective Vulnerability of Brainstem Nuclei in Distinct Tauopathies: A Postmortem Study.
Eser RA, Ehrenberg AJ, Petersen C, Dunlop S, Mejia MB, Suemoto CK, Walsh CM, Rajana H, Oh J, Theofilas P, Seeley WW, Miller BL, Neylan TC, Heinsen H, Grinberg LT. Eser RA, et al. Among authors: heinsen h. J Neuropathol Exp Neurol. 2018 Feb 1;77(2):149-161. doi: 10.1093/jnen/nlx113. J Neuropathol Exp Neurol. 2018. PMID: 29304218 Free PMC article.
On the origin of tau seeding activity in Alzheimer's disease.
Heinsen H, Grinberg LT. Heinsen H, et al. Acta Neuropathol. 2018 Nov;136(5):815-817. doi: 10.1007/s00401-018-1890-3. Epub 2018 Jul 23. Acta Neuropathol. 2018. PMID: 30039213 Free PMC article. No abstract available.
The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?
Grinberg LT, Rüb U, Ferretti RE, Nitrini R, Farfel JM, Polichiso L, Gierga K, Jacob-Filho W, Heinsen H; Brazilian Brain Bank Study Group. Grinberg LT, et al. Among authors: heinsen h. Neuropathol Appl Neurobiol. 2009 Aug;35(4):406-16. doi: 10.1111/j.1365-2990.2009.00997.x. Neuropathol Appl Neurobiol. 2009. PMID: 19508444
Argyrophilic Grain Disease: Demographics, Clinical, and Neuropathological Features From a Large Autopsy Study.
Rodriguez RD, Suemoto CK, Molina M, Nascimento CF, Leite RE, de Lucena Ferretti-Rebustini RE, Farfel JM, Heinsen H, Nitrini R, Ueda K, Pasqualucci CA, Jacob-Filho W, Yaffe K, Grinberg LT. Rodriguez RD, et al. Among authors: heinsen h. J Neuropathol Exp Neurol. 2016 Jul;75(7):628-35. doi: 10.1093/jnen/nlw034. Epub 2016 Jun 9. J Neuropathol Exp Neurol. 2016. PMID: 27283329 Free PMC article.
Profound degeneration of wake-promoting neurons in Alzheimer's disease.
Oh J, Eser RA, Ehrenberg AJ, Morales D, Petersen C, Kudlacek J, Dunlop SR, Theofilas P, Resende EDPF, Cosme C, Alho EJL, Spina S, Walsh CM, Miller BL, Seeley WW, Bittencourt JC, Neylan TC, Heinsen H, Grinberg LT. Oh J, et al. Among authors: heinsen h. Alzheimers Dement. 2019 Oct;15(10):1253-1263. doi: 10.1016/j.jalz.2019.06.3916. Epub 2019 Aug 12. Alzheimers Dement. 2019. PMID: 31416793 Free PMC article.
Molecular characterization of selectively vulnerable neurons in Alzheimer's disease.
Leng K, Li E, Eser R, Piergies A, Sit R, Tan M, Neff N, Li SH, Rodriguez RD, Suemoto CK, Leite REP, Ehrenberg AJ, Pasqualucci CA, Seeley WW, Spina S, Heinsen H, Grinberg LT, Kampmann M. Leng K, et al. Among authors: heinsen h. Nat Neurosci. 2021 Feb;24(2):276-287. doi: 10.1038/s41593-020-00764-7. Epub 2021 Jan 11. Nat Neurosci. 2021. PMID: 33432193 Free PMC article.
195 results