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MT5-MMP Promotes Alzheimer's Pathogenesis in the Frontal Cortex of 5xFAD Mice and APP Trafficking in vitro.
Baranger K, Bonnet AE, Girard SD, Paumier JM, García-González L, Elmanaa W, Bernard A, Charrat E, Stephan D, Bauer C, Moschke K, Lichtenthaler SF, Roman FS, Checler F, Khrestchatisky M, Rivera S. Baranger K, et al. Front Mol Neurosci. 2017 Jan 10;9:163. doi: 10.3389/fnmol.2016.00163. eCollection 2016. Front Mol Neurosci. 2017. PMID: 28119565 Free PMC article.
MT5-MMP is a new pro-amyloidogenic proteinase that promotes amyloid pathology and cognitive decline in a transgenic mouse model of Alzheimer's disease.
Baranger K, Marchalant Y, Bonnet AE, Crouzin N, Carrete A, Paumier JM, Py NA, Bernard A, Bauer C, Charrat E, Moschke K, Seiki M, Vignes M, Lichtenthaler SF, Checler F, Khrestchatisky M, Rivera S. Baranger K, et al. Cell Mol Life Sci. 2016 Jan;73(1):217-36. doi: 10.1007/s00018-015-1992-1. Epub 2015 Jul 23. Cell Mol Life Sci. 2016. PMID: 26202697 Free PMC article.
Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer's disease.
Giannoni P, Gaven F, de Bundel D, Baranger K, Marchetti-Gauthier E, Roman FS, Valjent E, Marin P, Bockaert J, Rivera S, Claeysen S. Giannoni P, et al. Among authors: baranger k. Front Aging Neurosci. 2013 Dec 24;5:96. doi: 10.3389/fnagi.2013.00096. eCollection 2013. Front Aging Neurosci. 2013. PMID: 24399967 Free PMC article.
Chronic treatments with a 5-HT4 receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimer's disease.
Baranger K, Giannoni P, Girard SD, Girot S, Gaven F, Stephan D, Migliorati M, Khrestchatisky M, Bockaert J, Marchetti-Gauthier E, Rivera S, Claeysen S, Roman FS. Baranger K, et al. Neuropharmacology. 2017 Nov;126:128-141. doi: 10.1016/j.neuropharm.2017.08.031. Epub 2017 Aug 26. Neuropharmacology. 2017. PMID: 28844596
37 results