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Design, Synthesis, and Antimicrobial Evaluation of a Novel Bone-Targeting Bisphosphonate-Ciprofloxacin Conjugate for the Treatment of Osteomyelitis Biofilms.
Sedghizadeh PP, Sun S, Junka AF, Richard E, Sadrerafi K, Mahabady S, Bakhshalian N, Tjokro N, Bartoszewicz M, Oleksy M, Szymczyk P, Lundy MW, Neighbors JD, Russell RG, McKenna CE, Ebetino FH. Sedghizadeh PP, et al. Among authors: russell rg. J Med Chem. 2017 Mar 23;60(6):2326-2343. doi: 10.1021/acs.jmedchem.6b01615. Epub 2017 Feb 13. J Med Chem. 2017. PMID: 28121436 Free PMC article.
Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine.
Sun S, Błażewska KM, Kadina AP, Kashemirov BA, Duan X, Triffitt JT, Dunford JE, Russell RG, Ebetino FH, Roelofs AJ, Coxon FP, Lundy MW, McKenna CE. Sun S, et al. Among authors: russell rg. Bioconjug Chem. 2016 Feb 17;27(2):329-40. doi: 10.1021/acs.bioconjchem.5b00369. Epub 2015 Dec 8. Bioconjug Chem. 2016. PMID: 26646666 Free PMC article.
Bisphosphonates for delivering drugs to bone.
Sun S, Tao J, Sedghizadeh PP, Cherian P, Junka AF, Sodagar E, Xing L, Boeckman RK Jr, Srinivasan V, Yao Z, Boyce BF, Lipe B, Neighbors JD, Russell RGG, McKenna CE, Ebetino FH. Sun S, et al. Br J Pharmacol. 2021 May;178(9):2008-2025. doi: 10.1111/bph.15251. Epub 2021 Apr 10. Br J Pharmacol. 2021. PMID: 32876338 Free PMC article. Review.
The Pharmacological Profile of a Novel Highly Potent Bisphosphonate, OX14 (1-Fluoro-2-(Imidazo-[1,2-α]Pyridin-3-yl)-Ethyl-Bisphosphonate).
Lawson MA, Ebetino FH, Mazur A, Chantry AD, Paton-Hough J, Evans HR, Lath D, Tsoumpra MK, Lundy MW, Dobson RL, Quijano M, Kwaasi AA, Dunford JE, Duan X, Triffitt JT, Jeans G, Russell RGG. Lawson MA, et al. J Bone Miner Res. 2017 Sep;32(9):1860-1869. doi: 10.1002/jbmr.3138. Epub 2017 Apr 21. J Bone Miner Res. 2017. PMID: 28337806 Free PMC article.
Bisphosphonate binding affinity affects drug distribution in both intracortical and trabecular bone of rabbits.
Turek J, Ebetino FH, Lundy MW, Sun S, Kashemirov BA, McKenna CE, Gallant MA, Plotkin LI, Bellido T, Duan X, Triffitt JT, Russell RG, Burr DB, Allen MR. Turek J, et al. Among authors: russell rg. Calcif Tissue Int. 2012 Mar;90(3):202-10. doi: 10.1007/s00223-012-9570-0. Epub 2012 Jan 17. Calcif Tissue Int. 2012. PMID: 22249525 Free PMC article.
503 results