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Page 1
Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.
Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AAB, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, Alexandrov K, Black BL, Hogan BM, De Val S, Capon RJ, Carroll JS, Bailey TL, Koopman P, Jauch R, Cooper MA, Gambin Y, Francois M. Overman J, et al. Among authors: jauch r. Elife. 2017 Jan 31;6:e21221. doi: 10.7554/eLife.21221. Elife. 2017. PMID: 28137359 Free PMC article.
The homeodomain of Oct4 is a dimeric binder of methylated CpG elements.
Tan DS, Cheung SL, Gao Y, Weinbuch M, Hu H, Shi L, Ti SC, Hutchins AP, Cojocaru V, Jauch R. Tan DS, et al. Among authors: jauch r. Nucleic Acids Res. 2023 Feb 22;51(3):1120-1138. doi: 10.1093/nar/gkac1262. Nucleic Acids Res. 2023. PMID: 36631980 Free PMC article.
Highly cooperative chimeric super-SOX induces naive pluripotency across species.
MacCarthy CM, Wu G, Malik V, Menuchin-Lasowski Y, Velychko T, Keshet G, Fan R, Bedzhov I, Church GM, Jauch R, Cojocaru V, Schöler HR, Velychko S. MacCarthy CM, et al. Among authors: jauch r. Cell Stem Cell. 2024 Jan 4;31(1):127-147.e9. doi: 10.1016/j.stem.2023.11.010. Epub 2023 Dec 22. Cell Stem Cell. 2024. PMID: 38141611 Free article.
Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction.
Klaus M, Prokoph N, Girbig M, Wang X, Huang YH, Srivastava Y, Hou L, Narasimhan K, Kolatkar PR, Francois M, Jauch R. Klaus M, et al. Among authors: jauch r. Nucleic Acids Res. 2016 May 5;44(8):3922-35. doi: 10.1093/nar/gkw130. Epub 2016 Mar 2. Nucleic Acids Res. 2016. PMID: 26939885 Free PMC article.
Small-Molecule Inhibitors of the SOX18 Transcription Factor.
Fontaine F, Overman J, Moustaqil M, Mamidyala S, Salim A, Narasimhan K, Prokoph N, Robertson AAB, Lua L, Alexandrov K, Koopman P, Capon RJ, Sierecki E, Gambin Y, Jauch R, Cooper MA, Zuegg J, Francois M. Fontaine F, et al. Among authors: jauch r. Cell Chem Biol. 2017 Mar 16;24(3):346-359. doi: 10.1016/j.chembiol.2017.01.003. Epub 2017 Feb 2. Cell Chem Biol. 2017. PMID: 28163017 Free article.
Evolutionary Landscape of SOX Genes to Inform Genotype-to-Phenotype Relationships.
Underwood A, Rasicci DT, Hinds D, Mitchell JT, Zieba JK, Mills J, Arnold NE, Cook TW, Moustaqil M, Gambin Y, Sierecki E, Fontaine F, Vanderweele S, Das AS, Cvammen W, Sirpilla O, Soehnlen X, Bricker K, Alokaili M, Green M, Heeringa S, Wilstermann AM, Freeland TM, Qutob D, Milsted A, Jauch R, Triche TJ Jr, Krawczyk CM, Bupp CP, Rajasekaran S, Francois M, Prokop JW. Underwood A, et al. Among authors: jauch r. Genes (Basel). 2023 Jan 14;14(1):222. doi: 10.3390/genes14010222. Genes (Basel). 2023. PMID: 36672963 Free PMC article.
SOX17 in cellular reprogramming and cancer.
Tan DS, Holzner M, Weng M, Srivastava Y, Jauch R. Tan DS, et al. Among authors: jauch r. Semin Cancer Biol. 2020 Dec;67(Pt 1):65-73. doi: 10.1016/j.semcancer.2019.08.008. Epub 2019 Aug 13. Semin Cancer Biol. 2020. PMID: 31419525 Review.
114 results