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Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability.
Gillinder KR, Ilsley MD, Nébor D, Sachidanandam R, Lajoie M, Magor GW, Tallack MR, Bailey T, Landsberg MJ, Mackay JP, Parker MW, Miles LA, Graber JH, Peters LL, Bieker JJ, Perkins AC. Gillinder KR, et al. Among authors: parker mw. Nucleic Acids Res. 2017 Feb 17;45(3):1130-1143. doi: 10.1093/nar/gkw1014. Nucleic Acids Res. 2017. PMID: 28180284 Free PMC article.
Copper binding to the Alzheimer's disease amyloid precursor protein.
Kong GK, Miles LA, Crespi GA, Morton CJ, Ng HL, Barnham KJ, McKinstry WJ, Cappai R, Parker MW. Kong GK, et al. Among authors: parker mw. Eur Biophys J. 2008 Mar;37(3):269-79. doi: 10.1007/s00249-007-0234-3. Epub 2007 Nov 21. Eur Biophys J. 2008. PMID: 18030462 Free PMC article. Review.
Direct involvement of the TEN domain at the active site of human telomerase.
Jurczyluk J, Nouwens AS, Holien JK, Adams TE, Lovrecz GO, Parker MW, Cohen SB, Bryan TM. Jurczyluk J, et al. Among authors: parker mw. Nucleic Acids Res. 2011 Mar;39(5):1774-88. doi: 10.1093/nar/gkq1083. Epub 2010 Nov 3. Nucleic Acids Res. 2011. PMID: 21051362 Free PMC article.
Structural approaches to probing metal interaction with proteins.
Parker LJ, Ascher DB, Gao C, Miles LA, Harris HH, Parker MW. Parker LJ, et al. Among authors: parker mw. J Inorg Biochem. 2012 Oct;115:138-47. doi: 10.1016/j.jinorgbio.2012.02.015. Epub 2012 Mar 3. J Inorg Biochem. 2012. PMID: 22437159 Review.
488 results