King EFB - Search Results

1

Simplifying nature: Towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins.

Gould ER, King EFB, Menzies SK, Fraser AL, Tulloch LB, Zacharova MK, Smith TK, Florence GJ. Gould ER, et al. Among authors: king efb. Bioorg Med Chem. 2017 Nov 15;25(22):6126-6136. doi: 10.1016/j.bmc.2017.01.021. Epub 2017 Jan 28. Bioorg Med Chem. 2017. PMID: 28185724

2

Development of Simplified Heterocyclic Acetogenin Analogues as Potent and Selective Trypanosoma brucei Inhibitors.

Florence GJ, Fraser AL, Gould ER, King EF, Menzies SK, Morris JC, Thomson MI, Tulloch LB, Zacharova MK, Smith TK. Florence GJ, et al. ChemMedChem. 2016 Jul 19;11(14):1503-6. doi: 10.1002/cmdc.201600210. Epub 2016 Jun 10. ChemMedChem. 2016. PMID: 27283448 Free PMC article.

3

Non-natural acetogenin analogues as potent Trypanosoma brucei inhibitors.

Florence GJ, Fraser AL, Gould ER, King EF, Menzies SK, Morris JC, Tulloch LB, Smith TK. Florence GJ, et al. ChemMedChem. 2014 Nov;9(11):2548-56. doi: 10.1002/cmdc.201402272. Epub 2014 Aug 21. ChemMedChem. 2014. PMID: 25145275 Free PMC article.

4

Design and Synthesis of Broad Spectrum Trypanosomatid Selective Inhibitors.

Fraser AL, Menzies SK, King EFB, Tulloch LB, Gould ER, Zacharova MK, Smith TK, Florence GJ. Fraser AL, et al. Among authors: king efb. ACS Infect Dis. 2018 Apr 13;4(4):560-567. doi: 10.1021/acsinfecdis.7b00187. Epub 2018 Jan 19. ACS Infect Dis. 2018. PMID: 29313667

5

Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues.

Tulloch LB, Menzies SK, Fraser AL, Gould ER, King EF, Zacharova MK, Florence GJ, Smith TK. Tulloch LB, et al. PLoS Negl Trop Dis. 2017 Sep 5;11(9):e0005886. doi: 10.1371/journal.pntd.0005886. eCollection 2017 Sep. PLoS Negl Trop Dis. 2017. PMID: 28873407 Free PMC article.

6

Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase.

Zacharova MK, Tulloch LB, Gould ER, Fraser AL, King EF, Menzies SK, Smith TK, Florence GJ. Zacharova MK, et al. European J Org Chem. 2019 Sep 1;2019(31-32):5434-5440. doi: 10.1002/ejoc.201900541. Epub 2019 May 29. European J Org Chem. 2019. PMID: 31598093 Free PMC article.

7

Galactokinase-like protein from Leishmania donovani: Biochemical and structural characterization of a recombinant protein.

Baber H, Aghajani A, Gallimore BH, Bethel C, Hyatt JG, King EFB, Price HP, Maciej-Hulme ML, Sari S, Winter A. Baber H, et al. Among authors: king efb. Biochimie. 2024 Aug;223:31-40. doi: 10.1016/j.biochi.2024.03.017. Epub 2024 Apr 4. Biochimie. 2024. PMID: 38579894 Free article.

8

Temperate Zone Plant Natural Products-A Novel Resource for Activity against Tropical Parasitic Diseases.

Hameed H, King EFB, Doleckova K, Bartholomew B, Hollinshead J, Mbye H, Ullah I, Walker K, Van Veelen M, Abou-Akkada SS, Nash RJ, Horrocks PD, Price HP. Hameed H, et al. Among authors: king efb. Pharmaceuticals (Basel). 2021 Mar 7;14(3):227. doi: 10.3390/ph14030227. Pharmaceuticals (Basel). 2021. PMID: 33800005 Free PMC article.

9

Metabolomic Analysis of Toxoplasma gondii Tachyzoites.

King EFB, Cobbold SA, Uboldi AD, Tonkin CJ, McConville MJ. King EFB, et al. Methods Mol Biol. 2020;2071:435-452. doi: 10.1007/978-1-4939-9857-9_22. Methods Mol Biol. 2020. PMID: 31758465

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