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Page 1
SMYD2 lysine methyltransferase regulates leukemia cell growth and regeneration after genotoxic stress.
Zipin-Roitman A, Aqaqe N, Yassin M, Biechonski S, Amar M, van Delft MF, Gan OI, McDermott SP, Buzina A, Ketela T, Shlush L, Xie S, Voisin V, Moffat J, Minden MD, Dick JE, Milyavsky M. Zipin-Roitman A, et al. Among authors: aqaqe n. Oncotarget. 2017 Mar 7;8(10):16712-16727. doi: 10.18632/oncotarget.15147. Oncotarget. 2017. PMID: 28187429 Free PMC article.
A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity.
Yassin M, Aqaqe N, Yassin AA, van Galen P, Kugler E, Bernstein BE, Koren-Michowitz M, Canaani J, Nagler A, Lechman ER, Dick JE, Wienholds E, Izraeli S, Milyavsky M. Yassin M, et al. Among authors: aqaqe n. Leukemia. 2019 Aug;33(8):2061-2077. doi: 10.1038/s41375-019-0386-z. Epub 2019 Jan 31. Leukemia. 2019. PMID: 30705411
Quercetin alters the DNA damage response in human hematopoietic stem and progenitor cells via TopoII- and PI3K-dependent mechanisms synergizing in leukemogenic rearrangements.
Biechonski S, Gourevich D, Rall M, Aqaqe N, Yassin M, Zipin-Roitman A, Trakhtenbrot L, Olender L, Raz Y, Jaffa AJ, Grisaru D, Wiesmuller L, Elad D, Milyavsky M. Biechonski S, et al. Among authors: aqaqe n. Int J Cancer. 2017 Feb 15;140(4):864-876. doi: 10.1002/ijc.30497. Epub 2016 Nov 22. Int J Cancer. 2017. PMID: 27813122
Attenuated DNA damage responses and increased apoptosis characterize human hematopoietic stem cells exposed to irradiation.
Biechonski S, Olender L, Zipin-Roitman A, Yassin M, Aqaqe N, Marcu-Malina V, Rall-Scharpf M, Trottier M, Meyn MS, Wiesmüller L, Beider K, Raz Y, Grisaru D, Nagler A, Milyavsky M. Biechonski S, et al. Among authors: aqaqe n. Sci Rep. 2018 Apr 17;8(1):6071. doi: 10.1038/s41598-018-24440-w. Sci Rep. 2018. PMID: 29666389 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 36163769
Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid.
Pesakhov S, Nachliely M, Barvish Z, Aqaqe N, Schwartzman B, Voronov E, Sharoni Y, Studzinski GP, Fishman D, Danilenko M. Pesakhov S, et al. Among authors: aqaqe n. Oncotarget. 2016 May 31;7(22):31847-61. doi: 10.18632/oncotarget.7240. Oncotarget. 2016. PMID: 26870993 Free PMC article.
The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG.
Kugler E, Madiwale S, Yong D, Thoms JAI, Birger Y, Sykes DB, Schmoellerl J, Drakul A, Priebe V, Yassin M, Aqaqe N, Rein A, Fishman H, Geron I, Chen CW, Raught B, Liu Q, Ogana H, Liedke E, Bourquin JP, Zuber J, Milyavsky M, Pimanda J, Privé GG, Izraeli S. Kugler E, et al. Among authors: aqaqe n. Nat Commun. 2023 Sep 21;14(1):5871. doi: 10.1038/s41467-023-41067-2. Nat Commun. 2023. PMID: 37735473 Free PMC article.