Kelly PS - Search Results

1

Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells.

Kelly PS, Clarke C, Costello A, Monger C, Meiller J, Dhiman H, Borth N, Betenbaugh MJ, Clynes M, Barron N. Kelly PS, et al. Metab Eng. 2017 May;41:11-22. doi: 10.1016/j.ymben.2017.02.001. Epub 2017 Feb 8. Metab Eng. 2017. PMID: 28188893

2

MicroRNAs: tiny targets for engineering CHO cell phenotypes?

Barron N, Sanchez N, Kelly P, Clynes M. Barron N, et al. Biotechnol Lett. 2011 Jan;33(1):11-21. doi: 10.1007/s10529-010-0415-5. Epub 2010 Sep 25. Biotechnol Lett. 2011. PMID: 20872159 Review.

3

Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate.

Clarke C, Henry M, Doolan P, Kelly S, Aherne S, Sanchez N, Kelly P, Kinsella P, Breen L, Madden SF, Zhang L, Leonard M, Clynes M, Meleady P, Barron N. Clarke C, et al. BMC Genomics. 2012 Nov 21;13:656. doi: 10.1186/1471-2164-13-656. BMC Genomics. 2012. PMID: 23170974 Free PMC article.

4

CHO cell culture longevity and recombinant protein yield are enhanced by depletion of miR-7 activity via sponge decoy vectors.

Sanchez N, Kelly P, Gallagher C, Lao NT, Clarke C, Clynes M, Barron N. Sanchez N, et al. Biotechnol J. 2014 Mar;9(3):396-404. doi: 10.1002/biot.201300325. Epub 2013 Dec 10. Biotechnol J. 2014. PMID: 24166820

5

Conserved microRNA function as a basis for Chinese hamster ovary cell engineering.

Kelly PS, Gallagher C, Clynes M, Barron N. Kelly PS, et al. Biotechnol Lett. 2015 Apr;37(4):787-98. doi: 10.1007/s10529-014-1751-7. Epub 2014 Dec 21. Biotechnol Lett. 2015. PMID: 25527440

6

Towards next generation CHO cell biology: Bioinformatics methods for RNA-Seq-based expression profiling.

Monger C, Kelly PS, Gallagher C, Clynes M, Barron N, Clarke C. Monger C, et al. Among authors: kelly ps. Biotechnol J. 2015 Jul;10(7):950-66. doi: 10.1002/biot.201500107. Epub 2015 Jun 9. Biotechnol J. 2015. PMID: 26058739 Review.

7

Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype.

Kelly PS, Breen L, Gallagher C, Kelly S, Henry M, Lao NT, Meleady P, O'Gorman D, Clynes M, Barron N. Kelly PS, et al. Biotechnol J. 2015 Jul;10(7):1029-40. doi: 10.1002/biot.201500101. Epub 2015 Jun 24. Biotechnol J. 2015. PMID: 26097147

8

Process-relevant concentrations of the leachable bDtBPP impact negatively on CHO cell production characteristics.

Kelly PS, McSweeney S, Coleman O, Carillo S, Henry M, Chandran D, Kellett A, Bones J, Clynes M, Meleady P, Barron N. Kelly PS, et al. Biotechnol Prog. 2016 Nov;32(6):1547-1558. doi: 10.1002/btpr.2345. Epub 2016 Sep 4. Biotechnol Prog. 2016. PMID: 27557043

9

Selection of High-Producing Clones Using FACS for CHO Cell Line Development.

Gallagher C, Kelly PS. Gallagher C, et al. Among authors: kelly ps. Methods Mol Biol. 2017;1603:143-152. doi: 10.1007/978-1-4939-6972-2_9. Methods Mol Biol. 2017. PMID: 28493128

10

miR-CATCH Identifies Biologically Active miRNA Regulators of the Pro-Survival Gene XIAP, in Chinese Hamster Ovary Cells.

Griffith A, Kelly PS, Vencken S, Lao NT, Greene CM, Clynes M, Barron N. Griffith A, et al. Among authors: kelly ps. Biotechnol J. 2018 Mar;13(3):e1700299. doi: 10.1002/biot.201700299. Epub 2017 Oct 30. Biotechnol J. 2018. PMID: 28976632

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