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Isolevuglandins as a gauge of lipid peroxidation in human tumors.
Yan HP, Roberts LJ, Davies SS, Pohlmann P, Parl FF, Estes S, Maeng J, Parker B, Mernaugh R. Yan HP, et al. Among authors: maeng j. Free Radic Biol Med. 2017 May;106:62-68. doi: 10.1016/j.freeradbiomed.2017.02.020. Epub 2017 Feb 9. Free Radic Biol Med. 2017. PMID: 28189846 Free PMC article.
Development of a Series of (1-Benzyl-3-(6-methoxypyrimidin-3-yl)-5-(trifluoromethoxy)-1H-indol-2-yl)methanols as Selective Protease Activated Receptor 4 (PAR4) Antagonists with in Vivo Utility and Activity Against γ-Thrombin.
Temple KJ, Duvernay MT, Young SE, Wen W, Wu W, Maeng JG, Blobaum AL, Stauffer SR, Hamm HE, Lindsley CW. Temple KJ, et al. Among authors: maeng jg. J Med Chem. 2016 Aug 25;59(16):7690-5. doi: 10.1021/acs.jmedchem.6b00928. Epub 2016 Aug 8. J Med Chem. 2016. PMID: 27482618 Free PMC article.
Discovery and Optimization of a Novel Series of Competitive and Central Nervous System-Penetrant Protease-Activated Receptor 4 (PAR4) Inhibitors.
Bertron JL, Duvernay MT, Mitchell SG, Smith ST, Maeng JG, Blobaum AL, Davis DC, Meiler J, Hamm HE, Lindsley CW. Bertron JL, et al. Among authors: maeng jg. ACS Chem Neurosci. 2021 Dec 15;12(24):4524-4534. doi: 10.1021/acschemneuro.1c00557. Epub 2021 Dec 2. ACS Chem Neurosci. 2021. PMID: 34855359 Free PMC article.
Epigenetic therapy potentiates transposable element transcription to create tumor-enriched antigens in glioblastoma cells.
Jang HJ, Shah NM, Maeng JH, Liang Y, Basri NL, Ge J, Qu X, Mahlokozera T, Tzeng SC, Williams RB, Moore MJ, Annamalai D, Chen JY, Lee HJ, DeSouza PA, Li D, Xing X, Kim AH, Wang T. Jang HJ, et al. Among authors: maeng jh. Nat Genet. 2024 Sep;56(9):1903-1913. doi: 10.1038/s41588-024-01880-x. Epub 2024 Sep 2. Nat Genet. 2024. PMID: 39223316
In-depth organoid profiling of pancreatic cancer.
Maeng JE, Ku JL. Maeng JE, et al. Nat Rev Cancer. 2024 Sep;24(9):596. doi: 10.1038/s41568-024-00726-2. Nat Rev Cancer. 2024. PMID: 38982147 No abstract available.
175 results