Heise T - Search Results

1

Steering Siglec-Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry.

Büll C, Heise T, van Hilten N, Pijnenborg JF, Bloemendal VR, Gerrits L, Kers-Rebel ED, Ritschel T, den Brok MH, Adema GJ, Boltje TJ. Büll C, et al. Among authors: heise t. Angew Chem Int Ed Engl. 2017 Mar 13;56(12):3309-3313. doi: 10.1002/anie.201612193. Epub 2017 Feb 14. Angew Chem Int Ed Engl. 2017. PMID: 28194834

2

Sialic Acid Mimetics to Target the Sialic Acid-Siglec Axis.

Büll C, Heise T, Adema GJ, Boltje TJ. Büll C, et al. Among authors: heise t. Trends Biochem Sci. 2016 Jun;41(6):519-531. doi: 10.1016/j.tibs.2016.03.007. Epub 2016 Apr 13. Trends Biochem Sci. 2016. PMID: 27085506 Review.

3

Disease mutations in CMP-sialic acid transporter SLC35A1 result in abnormal α-dystroglycan O-mannosylation, independent from sialic acid.

Riemersma M, Sandrock J, Boltje TJ, Büll C, Heise T, Ashikov A, Adema GJ, van Bokhoven H, Lefeber DJ. Riemersma M, et al. Among authors: heise t. Hum Mol Genet. 2015 Apr 15;24(8):2241-6. doi: 10.1093/hmg/ddu742. Epub 2014 Dec 30. Hum Mol Genet. 2015. PMID: 25552652

4

Sialic Acid Glycoengineering Using an Unnatural Sialic Acid for the Detection of Sialoglycan Biosynthesis Defects and On-Cell Synthesis of Siglec Ligands.

Büll C, Heise T, Beurskens DM, Riemersma M, Ashikov A, Rutjes FP, van Kuppevelt TH, Lefeber DJ, den Brok MH, Adema GJ, Boltje TJ. Büll C, et al. Among authors: heise t. ACS Chem Biol. 2015 Oct 16;10(10):2353-63. doi: 10.1021/acschembio.5b00501. Epub 2015 Aug 10. ACS Chem Biol. 2015. PMID: 26258433

5

Metabolic sialic acid blockade lowers the activation threshold of moDCs for TLR stimulation.

Büll C, Collado-Camps E, Kers-Rebel ED, Heise T, Søndergaard JN, den Brok MH, Schulte BM, Boltje TJ, Adema GJ. Büll C, et al. Among authors: heise t. Immunol Cell Biol. 2017 Apr;95(4):408-415. doi: 10.1038/icb.2016.105. Epub 2016 Nov 22. Immunol Cell Biol. 2017. PMID: 27874015

6

Metabolic Oligosaccharide Engineering with Alkyne Sialic Acids Confers Neuraminidase Resistance and Inhibits Influenza Reproduction.

Heise T, Büll C, Beurskens DM, Rossing E, de Jonge MI, Adema GJ, Boltje TJ, Langereis JD. Heise T, et al. Bioconjug Chem. 2017 Jul 19;28(7):1811-1815. doi: 10.1021/acs.bioconjchem.7b00224. Epub 2017 Jun 27. Bioconjug Chem. 2017. PMID: 28635265 Free PMC article.

7

Sialic Acid Blockade Suppresses Tumor Growth by Enhancing T-cell-Mediated Tumor Immunity.

Büll C, Boltje TJ, Balneger N, Weischer SM, Wassink M, van Gemst JJ, Bloemendal VR, Boon L, van der Vlag J, Heise T, den Brok MH, Adema GJ. Büll C, et al. Among authors: heise t. Cancer Res. 2018 Jul 1;78(13):3574-3588. doi: 10.1158/0008-5472.CAN-17-3376. Epub 2018 Apr 27. Cancer Res. 2018. PMID: 29703719

8

Selective Inhibition of Sialic Acid-Based Molecular Mimicry in Haemophilus influenzae Abrogates Serum Resistance.

Heise T, Langereis JD, Rossing E, de Jonge MI, Adema GJ, Büll C, Boltje TJ. Heise T, et al. Cell Chem Biol. 2018 Oct 18;25(10):1279-1285.e8. doi: 10.1016/j.chembiol.2018.05.018. Epub 2018 Jul 5. Cell Chem Biol. 2018. PMID: 29983272 Free article.

9

Potent Metabolic Sialylation Inhibitors Based on C-5-Modified Fluorinated Sialic Acids.

Heise T, Pijnenborg JFA, Büll C, van Hilten N, Kers-Rebel ED, Balneger N, Elferink H, Adema GJ, Boltje TJ. Heise T, et al. J Med Chem. 2019 Jan 24;62(2):1014-1021. doi: 10.1021/acs.jmedchem.8b01757. Epub 2018 Dec 31. J Med Chem. 2019. PMID: 30543426 Free PMC article.

10

Combined sialic acid and histone deacetylase (HDAC) inhibitor treatment up-regulates the neuroblastoma antigen GD2.

van den Bijgaart RJE, Kroesen M, Wassink M, Brok IC, Kers-Rebel ED, Boon L, Heise T, van Scherpenzeel M, Lefeber DJ, Boltje TJ, den Brok MH, Hoogerbrugge PM, Büll C, Adema GJ. van den Bijgaart RJE, et al. Among authors: heise t. J Biol Chem. 2019 Mar 22;294(12):4437-4449. doi: 10.1074/jbc.RA118.002763. Epub 2019 Jan 22. J Biol Chem. 2019. PMID: 30670592 Free PMC article.

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