Zhang J - Search Results

1

Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function.

Nihira NT, Ogura K, Shimizu K, North BJ, Zhang J, Gao D, Inuzuka H, Wei W. Nihira NT, et al. Among authors: zhang j. Sci Signal. 2017 Feb 14;10(466):eaai8026. doi: 10.1126/scisignal.aai8026. Sci Signal. 2017. PMID: 28196907 Free PMC article.

2

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis.

Zhang J, Wan L, Dai X, Sun Y, Wei W. Zhang J, et al. Biochim Biophys Acta. 2014 Apr;1845(2):277-93. doi: 10.1016/j.bbcan.2014.02.001. Epub 2014 Feb 22. Biochim Biophys Acta. 2014. PMID: 24569229 Free PMC article. Review.

3

Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair.

Liu P, Gan W, Guo C, Xie A, Gao D, Guo J, Zhang J, Willis N, Su A, Asara JM, Scully R, Wei W. Liu P, et al. Among authors: zhang j. Mol Cell. 2015 Feb 19;57(4):648-661. doi: 10.1016/j.molcel.2015.01.005. Epub 2015 Feb 5. Mol Cell. 2015. PMID: 25661488 Free PMC article.

4

Targeting Cdc20 as a novel cancer therapeutic strategy.

Wang L, Zhang J, Wan L, Zhou X, Wang Z, Wei W. Wang L, et al. Among authors: zhang j. Pharmacol Ther. 2015 Jul;151:141-51. doi: 10.1016/j.pharmthera.2015.04.002. Epub 2015 Apr 4. Pharmacol Ther. 2015. PMID: 25850036 Free PMC article. Review.

5

PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.

Liu P, Gan W, Chin YR, Ogura K, Guo J, Zhang J, Wang B, Blenis J, Cantley LC, Toker A, Su B, Wei W. Liu P, et al. Among authors: zhang j. Cancer Discov. 2015 Nov;5(11):1194-209. doi: 10.1158/2159-8290.CD-15-0460. Epub 2015 Aug 20. Cancer Discov. 2015. PMID: 26293922 Free PMC article.

6

The E3 ligase APC/C(Cdh1) promotes ubiquitylation-mediated proteolysis of PAX3 to suppress melanocyte proliferation and melanoma growth.

Cao J, Dai X, Wan L, Wang H, Zhang J, Goff PS, Sviderskaya EV, Xuan Z, Xu Z, Xu X, Hinds P, Flaherty KT, Faller DV, Goding CR, Wang Y, Wei W, Cui R. Cao J, et al. Among authors: zhang j. Sci Signal. 2015 Sep 1;8(392):ra87. doi: 10.1126/scisignal.aab1995. Sci Signal. 2015. PMID: 26329581

7

SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression.

Gan W, Dai X, Lunardi A, Li Z, Inuzuka H, Liu P, Varmeh S, Zhang J, Cheng L, Sun Y, Asara JM, Beck AH, Huang J, Pandolfi PP, Wei W. Gan W, et al. Among authors: zhang j. Mol Cell. 2015 Sep 17;59(6):917-30. doi: 10.1016/j.molcel.2015.07.026. Epub 2015 Sep 3. Mol Cell. 2015. PMID: 26344095 Free PMC article.

8

Cdh1 regulates craniofacial development via APC-dependent ubiquitination and activation of Goosecoid.

Shao R, Liu J, Yan G, Zhang J, Han Y, Guo J, Xu Z, Yuan Z, Liu J, Malumbres M, Wan L, Wei W, Zou W. Shao R, et al. Among authors: zhang j. Cell Res. 2016 Jun;26(6):699-712. doi: 10.1038/cr.2016.51. Epub 2016 Apr 29. Cell Res. 2016. PMID: 27126000 Free PMC article.

9

Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.

Zhang J, Xu K, Liu P, Geng Y, Wang B, Gan W, Guo J, Wu F, Chin YR, Berrios C, Lien EC, Toker A, DeCaprio JA, Sicinski P, Wei W. Zhang J, et al. Mol Cell. 2016 Jun 16;62(6):929-942. doi: 10.1016/j.molcel.2016.04.023. Epub 2016 May 26. Mol Cell. 2016. PMID: 27237051 Free PMC article.

10

Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner.

Liu J, Wan L, Liu J, Yuan Z, Zhang J, Guo J, Malumbres M, Liu J, Zou W, Wei W. Liu J, et al. Among authors: zhang j. Cell Discov. 2016 Feb 2;2:15044. doi: 10.1038/celldisc.2015.44. eCollection 2016. Cell Discov. 2016. PMID: 27462441 Free PMC article.

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