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Page 1
Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus.
Clee SM, Yandell BS, Schueler KM, Rabaglia ME, Richards OC, Raines SM, Kabara EA, Klass DM, Mui ET, Stapleton DS, Gray-Keller MP, Young MB, Stoehr JP, Lan H, Boronenkov I, Raess PW, Flowers MT, Attie AD. Clee SM, et al. Among authors: stapleton ds. Nat Genet. 2006 Jun;38(6):688-93. doi: 10.1038/ng1796. Epub 2006 May 7. Nat Genet. 2006. PMID: 16682971
A gene expression network model of type 2 diabetes links cell cycle regulation in islets with diabetes susceptibility.
Keller MP, Choi Y, Wang P, Davis DB, Rabaglia ME, Oler AT, Stapleton DS, Argmann C, Schueler KL, Edwards S, Steinberg HA, Chaibub Neto E, Kleinhanz R, Turner S, Hellerstein MK, Schadt EE, Yandell BS, Kendziorski C, Attie AD. Keller MP, et al. Among authors: stapleton ds. Genome Res. 2008 May;18(5):706-16. doi: 10.1101/gr.074914.107. Epub 2008 Mar 17. Genome Res. 2008. PMID: 18347327 Free PMC article.
Cholecystokinin is up-regulated in obese mouse islets and expands beta-cell mass by increasing beta-cell survival.
Lavine JA, Raess PW, Stapleton DS, Rabaglia ME, Suhonen JI, Schueler KL, Koltes JE, Dawson JA, Yandell BS, Samuelson LC, Beinfeld MC, Davis DB, Hellerstein MK, Keller MP, Attie AD. Lavine JA, et al. Among authors: stapleton ds. Endocrinology. 2010 Aug;151(8):3577-88. doi: 10.1210/en.2010-0233. Epub 2010 Jun 9. Endocrinology. 2010. PMID: 20534724 Free PMC article.
Loss of PDGF-B activity increases hepatic vascular permeability and enhances insulin sensitivity.
Raines SM, Richards OC, Schneider LR, Schueler KL, Rabaglia ME, Oler AT, Stapleton DS, Genové G, Dawson JA, Betsholtz C, Attie AD. Raines SM, et al. Among authors: stapleton ds. Am J Physiol Endocrinol Metab. 2011 Sep;301(3):E517-26. doi: 10.1152/ajpendo.00241.2011. Epub 2011 Jun 14. Am J Physiol Endocrinol Metab. 2011. PMID: 21673305 Free PMC article.
Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.
Bhatnagar S, Oler AT, Rabaglia ME, Stapleton DS, Schueler KL, Truchan NA, Worzella SL, Stoehr JP, Clee SM, Yandell BS, Keller MP, Thurmond DC, Attie AD. Bhatnagar S, et al. Among authors: stapleton ds. PLoS Genet. 2011 Oct;7(10):e1002323. doi: 10.1371/journal.pgen.1002323. Epub 2011 Oct 6. PLoS Genet. 2011. PMID: 21998599 Free PMC article.
Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ. Still AJ, et al. Among authors: stapleton ds. J Biol Chem. 2013 Sep 6;288(36):26209-26219. doi: 10.1074/jbc.M113.483396. Epub 2013 Jul 17. J Biol Chem. 2013. PMID: 23864654 Free PMC article.
SORCS1 is necessary for normal insulin secretory granule biogenesis in metabolically stressed β cells.
Kebede MA, Oler AT, Gregg T, Balloon AJ, Johnson A, Mitok K, Rabaglia M, Schueler K, Stapleton D, Thorstenson C, Wrighton L, Floyd BJ, Richards O, Raines S, Eliceiri K, Seidah NG, Rhodes C, Keller MP, Coon JL, Audhya A, Attie AD. Kebede MA, et al. J Clin Invest. 2014 Oct;124(10):4240-56. doi: 10.1172/JCI74072. Epub 2014 Aug 26. J Clin Invest. 2014. PMID: 25157818 Free PMC article.
36 results