Peschke M - Search Results

1

Chlorinated Glycopeptide Antibiotic Peptide Precursors Improve Cytochrome P450-Catalyzed Cyclization Cascade Efficiency.

Peschke M, Brieke C, Goode RJ, Schittenhelm RB, Cryle MJ. Peschke M, et al. Biochemistry. 2017 Mar 7;56(9):1239-1247. doi: 10.1021/acs.biochem.6b01102. Epub 2017 Feb 24. Biochemistry. 2017. PMID: 28218515

2

X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis.

Haslinger K, Peschke M, Brieke C, Maximowitsch E, Cryle MJ. Haslinger K, et al. Among authors: peschke m. Nature. 2015 May 7;521(7550):105-9. doi: 10.1038/nature14141. Epub 2015 Feb 9. Nature. 2015. PMID: 25686610

3

Sequential In Vitro Cyclization by Cytochrome P450 Enzymes of Glycopeptide Antibiotic Precursors Bearing the X-Domain from Nonribosomal Peptide Biosynthesis.

Brieke C, Peschke M, Haslinger K, Cryle MJ. Brieke C, et al. Among authors: peschke m. Angew Chem Int Ed Engl. 2015 Dec 21;54(52):15715-9. doi: 10.1002/anie.201507533. Epub 2015 Nov 9. Angew Chem Int Ed Engl. 2015. PMID: 26549530

4

Facile Synthetic Access to Glycopeptide Antibiotic Precursor Peptides for the Investigation of Cytochrome P450 Action in Glycopeptide Antibiotic Biosynthesis.

Brieke C, Kratzig V, Peschke M, Cryle MJ. Brieke C, et al. Among authors: peschke m. Methods Mol Biol. 2016;1401:85-102. doi: 10.1007/978-1-4939-3375-4_6. Methods Mol Biol. 2016. PMID: 26831703

5

Regulation of the P450 Oxygenation Cascade Involved in Glycopeptide Antibiotic Biosynthesis.

Peschke M, Haslinger K, Brieke C, Reinstein J, Cryle MJ. Peschke M, et al. J Am Chem Soc. 2016 Jun 1;138(21):6746-53. doi: 10.1021/jacs.6b00307. Epub 2016 May 23. J Am Chem Soc. 2016. PMID: 27213615

6

Understanding the crucial interactions between Cytochrome P450s and non-ribosomal peptide synthetases during glycopeptide antibiotic biosynthesis.

Peschke M, Gonsior M, Süssmuth RD, Cryle MJ. Peschke M, et al. Curr Opin Struct Biol. 2016 Dec;41:46-53. doi: 10.1016/j.sbi.2016.05.018. Epub 2016 Jun 9. Curr Opin Struct Biol. 2016. PMID: 27289043 Free article. Review.

7

More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH.

Ulrich V, Peschke M, Brieke C, Cryle MJ. Ulrich V, et al. Among authors: peschke m. Mol Biosyst. 2016 Oct 20;12(10):2992-3004. doi: 10.1039/c6mb00373g. Epub 2016 Aug 1. Mol Biosyst. 2016. PMID: 27477788

8

F-O-G Ring Formation in Glycopeptide Antibiotic Biosynthesis is Catalysed by OxyE.

Peschke M, Brieke C, Cryle MJ. Peschke M, et al. Sci Rep. 2016 Oct 18;6:35584. doi: 10.1038/srep35584. Sci Rep. 2016. PMID: 27752135 Free PMC article.

9

Catalytic promiscuity of glycopeptide N-methyltransferases enables bio-orthogonal labelling of biosynthetic intermediates.

Brieke C, Yim G, Peschke M, Wright GD, Cryle MJ. Brieke C, et al. Among authors: peschke m. Chem Commun (Camb). 2016 Nov 17;52(94):13679-13682. doi: 10.1039/c6cc06975d. Chem Commun (Camb). 2016. PMID: 27812569

10

The Thioesterase Domain in Glycopeptide Antibiotic Biosynthesis Is Selective for Cross-Linked Aglycones.

Peschke M, Brieke C, Heimes M, Cryle MJ. Peschke M, et al. ACS Chem Biol. 2018 Jan 19;13(1):110-120. doi: 10.1021/acschembio.7b00943. Epub 2017 Dec 11. ACS Chem Biol. 2018. PMID: 29192758

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