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Commanding CNS Invasion: GM-CSF.
Zhao J, Sun L, Li X. Zhao J, et al. Among authors: li x. Immunity. 2017 Feb 21;46(2):165-167. doi: 10.1016/j.immuni.2017.02.003. Immunity. 2017. PMID: 28228272 Free PMC article.
The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation.
Gulen MF, Kang Z, Bulek K, Youzhong W, Kim TW, Chen Y, Altuntas CZ, Sass Bak-Jensen K, McGeachy MJ, Do JS, Xiao H, Delgoffe GM, Min B, Powell JD, Tuohy VK, Cua DJ, Li X. Gulen MF, et al. Among authors: li x. Immunity. 2010 Jan 29;32(1):54-66. doi: 10.1016/j.immuni.2009.12.003. Epub 2010 Jan 7. Immunity. 2010. PMID: 20060329 Free PMC article.
CNS autoimmune inflammation: RICK must NOD!
Kang Z, Gulen MF, Li X. Kang Z, et al. Among authors: li x. Immunity. 2011 Jan 28;34(1):3-5. doi: 10.1016/j.immuni.2011.01.010. Immunity. 2011. PMID: 21272781 Free PMC article.
SIGIRR, a negative regulator of colon tumorigenesis.
Zhao J, Zepp J, Bulek K, Li X. Zhao J, et al. Among authors: li x. Drug Discov Today Dis Mech. 2011 Winter;8(3-4):e63-e69. doi: 10.1016/j.ddmec.2012.02.003. Epub 2012 Mar 15. Drug Discov Today Dis Mech. 2011. PMID: 22529873 Free PMC article.
Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance.
Gulen MF, Bulek K, Xiao H, Yu M, Gao J, Sun L, Beurel E, Kaidanovich-Beilin O, Fox PL, DiCorleto PE, Wang JA, Qin J, Wald DN, Woodgett JR, Jope RS, Carman J, Dongre A, Li X. Gulen MF, et al. Among authors: li x. Immunity. 2012 Nov 16;37(5):800-12. doi: 10.1016/j.immuni.2012.08.019. Epub 2012 Nov 8. Immunity. 2012. PMID: 23142783 Free PMC article.
Act1 mediates IL-17-induced EAE pathogenesis selectively in NG2+ glial cells.
Kang Z, Wang C, Zepp J, Wu L, Sun K, Zhao J, Chandrasekharan U, DiCorleto PE, Trapp BD, Ransohoff RM, Li X. Kang Z, et al. Among authors: li x. Nat Neurosci. 2013 Oct;16(10):1401-8. doi: 10.1038/nn.3505. Epub 2013 Sep 1. Nat Neurosci. 2013. PMID: 23995070 Free PMC article.
MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases.
Yu M, Zhou H, Zhao J, Xiao N, Roychowdhury S, Schmitt D, Hu B, Ransohoff RM, Harding CV, Hise AG, Hazen SL, DeFranco AL, Fox PL, Morton RE, Dicorleto PE, Febbraio M, Nagy LE, Smith JD, Wang JA, Li X. Yu M, et al. Among authors: li x. J Exp Med. 2014 May 5;211(5):887-907. doi: 10.1084/jem.20131314. Epub 2014 Apr 21. J Exp Med. 2014. PMID: 24752299 Free PMC article.
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