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Loss of tumor suppressor KDM6A amplifies PRC2-regulated transcriptional repression in bladder cancer and can be targeted through inhibition of EZH2.
Ler LD, Ghosh S, Chai X, Thike AA, Heng HL, Siew EY, Dey S, Koh LK, Lim JQ, Lim WK, Myint SS, Loh JL, Ong P, Sam XX, Huang D, Lim T, Tan PH, Nagarajan S, Cheng CW, Ho H, Ng LG, Yuen J, Lin PH, Chuang CK, Chang YH, Weng WH, Rozen SG, Tan P, Creasy CL, Pang ST, McCabe MT, Poon SL, Teh BT. Ler LD, et al. Among authors: chai x. Sci Transl Med. 2017 Feb 22;9(378):eaai8312. doi: 10.1126/scitranslmed.aai8312. Sci Transl Med. 2017. PMID: 28228601
Regulation of the boundaries of accessible chromatin.
Chai X, Nagarajan S, Kim K, Lee K, Choi JK. Chai X, et al. PLoS Genet. 2013;9(9):e1003778. doi: 10.1371/journal.pgen.1003778. Epub 2013 Sep 12. PLoS Genet. 2013. PMID: 24068952 Free PMC article.
Hypoxia enhances antibody-dependent dengue virus infection.
Gan ES, Cheong WF, Chan KR, Ong EZ, Chai X, Tan HC, Ghosh S, Wenk MR, Ooi EE. Gan ES, et al. Among authors: chai x. EMBO J. 2017 May 15;36(10):1348-1363. doi: 10.15252/embj.201695642. Epub 2017 Mar 20. EMBO J. 2017. PMID: 28320741 Free PMC article.
Exploring the underlying biology of intrinsic cardiorespiratory fitness through integrative analysis of genomic variants and muscle gene expression profiling.
Ghosh S, Hota M, Chai X, Kiranya J, Ghosh P, He Z, Ruiz-Ramie JJ, Sarzynski MA, Bouchard C. Ghosh S, et al. Among authors: chai x. J Appl Physiol (1985). 2019 May 1;126(5):1292-1314. doi: 10.1152/japplphysiol.00035.2018. Epub 2019 Jan 3. J Appl Physiol (1985). 2019. PMID: 30605401 Free PMC article.
2,021 results