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Page 1
Inactivation of Lsd1 triggers senescence in trophoblast stem cells by induction of Sirt4.
Castex J, Willmann D, Kanouni T, Arrigoni L, Li Y, Friedrich M, Schleicher M, Wöhrle S, Pearson M, Kraut N, Méret M, Manke T, Metzger E, Schüle R, Günther T. Castex J, et al. Among authors: gunther t. Cell Death Dis. 2017 Feb 23;8(2):e2631. doi: 10.1038/cddis.2017.48. Cell Death Dis. 2017. PMID: 28230862 Free PMC article.
LSD1 promotes oxidative metabolism of white adipose tissue.
Duteil D, Metzger E, Willmann D, Karagianni P, Friedrichs N, Greschik H, Günther T, Buettner R, Talianidis I, Metzger D, Schüle R. Duteil D, et al. Among authors: gunther t. Nat Commun. 2014 Jun 10;5:4093. doi: 10.1038/ncomms5093. Nat Commun. 2014. PMID: 24912735 Free PMC article.
The histone code reader Spin1 controls skeletal muscle development.
Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, Jung M, Metzger D, Manke T, Günther T, Schüle R. Greschik H, et al. Among authors: gunther t. Cell Death Dis. 2017 Nov 23;8(11):e3173. doi: 10.1038/cddis.2017.468. Cell Death Dis. 2017. PMID: 29168801 Free PMC article.
Selective targeting of the BRG/PB1 bromodomains impairs embryonic and trophoblast stem cell maintenance.
Fedorov O, Castex J, Tallant C, Owen DR, Martin S, Aldeghi M, Monteiro O, Filippakopoulos P, Picaud S, Trzupek JD, Gerstenberger BS, Bountra C, Willmann D, Wells C, Philpott M, Rogers C, Biggin PC, Brennan PE, Bunnage ME, Schüle R, Günther T, Knapp S, Müller S. Fedorov O, et al. Among authors: gunther t. Sci Adv. 2015 Nov 13;1(10):e1500723. doi: 10.1126/sciadv.1500723. eCollection 2015 Nov. Sci Adv. 2015. PMID: 26702435 Free PMC article.
Selective targeting of epigenetic reader domains.
Greschik H, Schüle R, Günther T. Greschik H, et al. Among authors: gunther t. Expert Opin Drug Discov. 2017 May;12(5):449-463. doi: 10.1080/17460441.2017.1303474. Epub 2017 Mar 14. Expert Opin Drug Discov. 2017. PMID: 28277835 Review.
Phosphorylation of histone H3T6 by PKCbeta(I) controls demethylation at histone H3K4.
Metzger E, Imhof A, Patel D, Kahl P, Hoffmeyer K, Friedrichs N, Müller JM, Greschik H, Kirfel J, Ji S, Kunowska N, Beisenherz-Huss C, Günther T, Buettner R, Schüle R. Metzger E, et al. Among authors: gunther t. Nature. 2010 Apr 1;464(7289):792-6. doi: 10.1038/nature08839. Epub 2010 Mar 14. Nature. 2010. PMID: 20228790
Fat or bone? A non-canonical decision.
Günther T, Schüle R. Günther T, et al. Nat Cell Biol. 2007 Nov;9(11):1229-31. doi: 10.1038/ncb1107-1229. Nat Cell Biol. 2007. PMID: 17975548 No abstract available.
520 results