Thurmond RL - Search Results

1

Clinical Development of Histamine H₄ Receptor Antagonists.

Thurmond RL, Venable J, Savall B, La D, Snook S, Dunford PJ, Edwards JP. Thurmond RL, et al. Handb Exp Pharmacol. 2017;241:301-320. doi: 10.1007/164_2016_130. Handb Exp Pharmacol. 2017. PMID: 28233185 Review.

2

Agonist/antagonist modulation in a series of 2-aryl benzimidazole H4 receptor ligands.

Savall BM, Edwards JP, Venable JD, Buzard DJ, Thurmond R, Hack M, McGovern P. Savall BM, et al. Bioorg Med Chem Lett. 2010 Jun 1;20(11):3367-71. doi: 10.1016/j.bmcl.2010.04.017. Epub 2010 Apr 11. Bioorg Med Chem Lett. 2010. PMID: 20452213

3

A potent and selective histamine H4 receptor antagonist with anti-inflammatory properties.

Thurmond RL, Desai PJ, Dunford PJ, Fung-Leung WP, Hofstra CL, Jiang W, Nguyen S, Riley JP, Sun S, Williams KN, Edwards JP, Karlsson L. Thurmond RL, et al. J Pharmacol Exp Ther. 2004 Apr;309(1):404-13. doi: 10.1124/jpet.103.061754. Epub 2004 Jan 13. J Pharmacol Exp Ther. 2004. PMID: 14722321

4

Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation.

Ling P, Ngo K, Nguyen S, Thurmond RL, Edwards JP, Karlsson L, Fung-Leung WP. Ling P, et al. Among authors: thurmond rl. Br J Pharmacol. 2004 May;142(1):161-71. doi: 10.1038/sj.bjp.0705729. Br J Pharmacol. 2004. PMID: 15131002 Free PMC article.

5

The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells.

Dunford PJ, O'Donnell N, Riley JP, Williams KN, Karlsson L, Thurmond RL. Dunford PJ, et al. Among authors: thurmond rl. J Immunol. 2006 Jun 1;176(11):7062-70. doi: 10.4049/jimmunol.176.11.7062. J Immunol. 2006. PMID: 16709868

6

The histamine H4 receptor in autoimmune disease.

Zhang M, Venable JD, Thurmond RL. Zhang M, et al. Among authors: thurmond rl. Expert Opin Investig Drugs. 2006 Nov;15(11):1443-52. doi: 10.1517/13543784.15.11.1443. Expert Opin Investig Drugs. 2006. PMID: 17040202 Review.

7

Histamine H4 receptor antagonists are superior to traditional antihistamines in the attenuation of experimental pruritus.

Dunford PJ, Williams KN, Desai PJ, Karlsson L, McQueen D, Thurmond RL. Dunford PJ, et al. Among authors: thurmond rl. J Allergy Clin Immunol. 2007 Jan;119(1):176-83. doi: 10.1016/j.jaci.2006.08.034. Epub 2006 Oct 13. J Allergy Clin Immunol. 2007. PMID: 17208599

8

The histamine H(4) receptor: a novel modulator of inflammatory and immune disorders.

Zhang M, Thurmond RL, Dunford PJ. Zhang M, et al. Among authors: thurmond rl. Pharmacol Ther. 2007 Mar;113(3):594-606. doi: 10.1016/j.pharmthera.2006.11.008. Epub 2006 Dec 28. Pharmacol Ther. 2007. PMID: 17275092 Review.

9

The role of histamine H1 and H4 receptors in allergic inflammation: the search for new antihistamines.

Thurmond RL, Gelfand EW, Dunford PJ. Thurmond RL, et al. Nat Rev Drug Discov. 2008 Jan;7(1):41-53. doi: 10.1038/nrd2465. Nat Rev Drug Discov. 2008. PMID: 18172439 Review.

10

The histamine H4 receptor mediates inflammation and pruritus in Th2-dependent dermal inflammation.

Cowden JM, Zhang M, Dunford PJ, Thurmond RL. Cowden JM, et al. Among authors: thurmond rl. J Invest Dermatol. 2010 Apr;130(4):1023-33. doi: 10.1038/jid.2009.358. Epub 2009 Nov 12. J Invest Dermatol. 2010. PMID: 19907432 Free article.

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